新型心肌损伤标志物在胸痛患者早期诊断中的应用  

Research progress on application of several new myocardial injury markers in early diagnosis of patients with chest pain

作　　者：张艳 王温琪 金慧敏 郑江花 ZHANG Yan;WANG Wenqi;JIN Huimin;ZHENG Jianghua(Department of Clinical Laboratory,Shanghai Pudong New District Zhoupu Hospital,Shanghai 201318,China)

机构地区：[1]上海市浦东新区(上海健康医学院附属)周浦医院医学检验科,上海市201318

出　　处：《中国动脉硬化杂志》2021年第8期722-724,共3页Chinese Journal of Arteriosclerosis

基　　金：国家自然科学基金面上项目(81372318);上海市浦东新区卫生和计划生育委员会领先人才培养计划(PWRL2017-07)。

摘　　要：急性冠状动脉综合征是一类心脏突发缺血性综合征。目前临床广泛使用的传统心肌损伤标志物如肌钙蛋白等在特异性、灵敏度以及信号时效性等方面存在局限性,致使急性胸痛患者误诊、漏诊或延误治疗而错过最佳抢救治疗时机。为此,研究人员近年来研究发现一些针对急性冠状动脉综合征患者具有早期诊断预测价值的新型心肌损伤标志物。本文将针对这些新型心肌损伤标志物在急性冠状动脉综合征患者早期诊断应用中的研究进展进行综述。Acute coronary syndrome is a kind of acute cardiac ischemic syndrome.At present,the traditional cardiac markers such as troponin are widely used in clinic,but have limitation of poor specificity,low sensitivity and signal timeliness.This leads to misdiagnosis,missed diagnosis or delayed treatment of patients with acute chest pain,and the best opportunity for rescue treatment is missed.To this end,researchers have found some novel biomarkers with early diagnostic and predictive value for myocardial injury in acute coronary syndrome in recent years.This review will summarize the research progress of these novel myocardial injury markers in the early diagnosis of acute coronary syndrome patients.

关 键 词：急性冠状动脉综合征 心肌损伤标志物 早期诊断 

分 类 号：R5[医药卫生—内科学]