尿11-脱氢血栓烷B2在急性冠脉综合征中的应用  

Application of Urine 11-dehydrothromboxane B2 in acute coronary syndromes

作　　者：韩雨晴 王凤超[1] HAN Yu-qing(The first affiliated hospital of Bengbu Medical College,Bengbu,Anhui,233000,China)

机构地区：[1]蚌埠医学院第一附属医院,安徽蚌埠233000

出　　处：《齐齐哈尔医学院学报》2021年第12期1066-1069,共4页Journal of Qiqihar Medical University

摘　　要：近年来,随着我国经济迅速发展,人们的生活方式、饮食习惯的改变及精神压力过大,急性冠状动脉综合征(ACS)的发病率整体呈上升趋势,尿11-脱氢血栓烷B2(11-dehydrothromboxane B2,11-DH-TXB2)可能对ACS的预防和评价阿司匹林的治疗效果颇有益处。尿11-DH-TXB2可以作为ACS的独立危险因素,同时亦可以检测患者是否存在阿司匹林抵抗,继而可以更好得发挥阿司匹林在心血管疾病治疗中的的抗血小板作用。本文对尿11-DH-TXB2在ACS的预防及治疗中的应用作如下论述。In recent years,with the rapid development of Chinese economy,lifestyle and dietary habits of peoplehave been greatly changed and too much mental stress.The incidence of acute coronary syndrome(ACS)is on the rise.Urinary 11-dehydrothromboxane B2(11-DH-TXB2)may be helpful in the prevention of ACS and the evaluation of the therapeutic effect of aspirin.Urine 11-DH-TXB2 could be used as an independent risk factor for ACS,and could also detect whether patients have aspirin resistance,so as to better play the anti-platelet effect of aspirin in the treatment of cardiovascular diseases.This article discusses the application of urine 11-DH-TXB2 in the prevention and treatment of ACS.

关 键 词：11-脱氢血栓烷B2 血栓素A2 急性冠脉综合征 阿司匹林抵抗 

分 类 号：R541.4[医药卫生—心血管疾病]