多频听觉稳态反应与切迹噪声掩蔽短纯音诱发的听性脑干反应对纯音听阈的预测  

Predicting pure-tone thresholds by multiple auditory steady-state response and tone burst-evoked auditory brainstem response in notched noise

作　　者：邹琦娟 倪道凤[2] 商莹莹[2] ZOU Qijuan;NI Daofeng;SHANG Yingying(Department of Otolaryngology Head and Neck Surgery,Beijing Tongren Hospital,Capital Medical University,Key Laboratory of Otolaryngology Head and Neck Surgery(Capital Medical University),Ministry of Education,Beijing,100730,China;Department of Otolaryngology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College,Beijing,100730,China)

机构地区：[1]首都医科大学附属北京同仁医院耳鼻咽喉头颈外科耳鼻咽喉头颈科学教育部重点实验室(首都医科大学),北京100730 [2]中国医学科学院北京协和医学院北京协和医院耳鼻喉科,北京100730

出　　处：《中国耳鼻咽喉头颈外科》2021年第6期352-355,共4页Chinese Archives of Otolaryngology-Head and Neck Surgery

摘　　要：目的在感音神经性听力损失(sensorineural hearing loss,SNHL)成年患者中通过回归方程,应用多频听觉稳态反应(auditory steady-state response,ASSR)和同侧切迹噪声(notched noise,NN)掩蔽短纯音诱发的听性脑干反应(NN-ABR)预测纯音听阈。方法 测试22例(30耳)SNHL成年患者的多频ASSR和NN-ABR反应阈,将其代入各自对纯音听阈的回归方程,将所得的预测听阈与实际纯音听阈进行比较。结果本组SNHL成年患者0.5、1、2、4 kHz的多频ASSR预测听阈与实际纯音听阈之差为(-1.37±10.6)、(-0.47±9.8)、(1.98±6.6)、(-3.8±11.4)dB;相应频率NN-ABR预测听阈与实际纯音听阈之差为(-0.32±9.6)、(1.4±7.9)、(0.18±5.7)、(-0.8±6.0)dB。协方差分析显示测试方法对预测结果无显著影响(F=0.669,P=0.415)。结论使用多频ASSR和NN-ABR反应阈通过回归方程预测纯音听阈均有较高的准确性。OBJECTIVE To predict pure-tone thresholds in sensorineural hearing loss(SNHL)adults,using thresholds of multiple auditory steady-state response(ASSR)and tone burst-evoked auditory brainstem response in notched noise(NN-ABR)via the regression equation.METHODS Multiple ASSR and NN-ABR thresholds of 22 SNHL adults(30 ears)were substituted in regression equations between auditory evoked response thresholds and pure-tone thresholds to obtain estimated pure-tone thresholds.The estimated thresholds were compared with the actual ones to evaluate the accuracy of ASSR and NN-ABR in predicting pure-tone thresholds.RESULTS Differences between ASSR-predicted and actual pure-tone thresholds in this SNHL adults group were(-1.37±10.6),(-0.47±9.8),(1.98±6.6),(-3.8±11.4)dB at 0.5,1,2,4 kHz respectively.Those for NN-ABR were(-0.32±9.6),(1.4±7.9),(0.18±5.7),(-0.8±6.0)dB respectively.Analysis of covariance showed that the test methods had no significant effect on the prediction(F=0.669,P-0.415).CONCLUSION Both ASSR and NN-ABR thresholds can accurately predict puretone thresholds via regression equations.

关 键 词：测听法 纯音 诱发电位 听觉 脑干 噪声 听阈 多频听觉稳态反应 

分 类 号：R764[医药卫生—耳鼻咽喉科]