双源CT对心脏周围脂肪组织与冠状动脉粥样硬化的相关性  

The Correlation between Epicardial Adipose Tissue and Coronary Artery Atherosclerosis with the Dual-source CT

作　　者：张文斌[1] 韩丹[1] 田扬[1] 赵卫[1] ZHANG Wen-bin;HAN Dan;TIAN Yang;ZHAO Wei(Dept.of Radiology,The 1st Affiliated Hospital of Kunming Medical University,Kunming Yunnan 650032,China)

机构地区：[1]昆明医科大学第一附属医院医学影像科,云南昆明650032

出　　处：《昆明医科大学学报》2021年第8期111-117,共7页Journal of Kunming Medical University

基　　金：云南省科技厅-昆明医科大学应用基础研究联合专项基金资助项目(2014FA013、2018FE001-041)。

摘　　要：目的探讨双源CT测量心周脂肪组织(pericardial adipose tissue,PAT)体积、心外膜脂肪组织(epicardial adipose tissue,EAT)体积、EAT/PAT比值,分析与冠状动脉粥样硬化程度的相关性。方法收集223例临床怀疑冠心病患者,所有患者均行双源CT冠状动脉造影检查。应用Circulation软件评价冠状动脉病变情况。分析PAT体积、EAT体积、EAT/PAT比值与性别,有、无冠状动脉粥样硬化及冠状动脉粥样硬化程度的相关性。结果有、无冠状动脉硬化组,PAT体积、EAT体积均无性别差异(P>0.05),EAT/PAT比值存在性别差异(P<0.05)。男、女性PAT体积、EAT体积、EAT/PAT比值与有、无冠状动脉粥样硬化成正相关(P<0.05);所有患者PAT体积、EAT体积、EAT/PAT比值与有、无冠状动脉粥样硬化均成正相关(P<0.05)。结论EAT体积较PAT体积与CAS相关性更高,而EAT/PAT较PAT体积、EAT体积与CAS具有更高的相关性,应能更准确地预测CHD。Objective To explore the correlation between adipose tissue around the heart(pericardial adipose tissue,PAT;epicardial adipose tissue,EAT)and severity of coronary artery atherosclerosis with the Dualsource CT.Methods 223 patients suspected with coronary artery disease underwent Dual-source CT coronary angiography were enrolled in this study.The severity of coronary artery atherosclerosis were evaluated by using Circulation software.The correlation between PAT volume,EAT volume,EAT/PAT ratio and gender,with or without coronary atherosclerosis and the degree of coronary atherosclerosis were analyzed.Results There was no gender difference in PAT volume and EAT volume between the two groups(P>0.05),and there was gender difference in EAT/PAT ratio between the two groups(P<0.05).PAT volume,EAT volume and EAT/PAT ratio were positively correlated with coronary atherosclerosis in males and females(P<0.05).PAT volume,EAT volume and EAT/PAT ratio were positively correlated with the presence and absence of coronary atherosclerosis in all patients(P<0.05).Concllision The correlation between EAT volume and CAS is higher than PAT volume,while the ratio of EAT/PAT has higher correlation with CAS than PAT volume and EAT volume,which should be able to predict CHD more accurately.

关 键 词：心周脂肪组织 心外膜脂肪组织 冠状动脉粥样硬化 体层摄影术 X-线计算机 

分 类 号：R445.3[医药卫生—影像医学与核医学]