加味桂枝加葛根汤治疗非特异性下腰痛寒湿证的临床研究  

Clinical Study on Modified Cassia Twig and Pueraria Decoction in the Treatment of Non-specific Low Back Pain Patients with Cold-Dampness Syndrome

作　　者：苏丽湘[1] 廖向荣[1] 林谦[1] 何剑荣[1] 黄培良[1] 丁有奕[1] 周树珊 黄少妮[1] 林丽莉[1] SU Li-xiang;LIAO Xiang-rong;LIN Qian;HE Jian-rong;HUANG Pei-liang;DING You-yi;ZHOU Shu-shan;HUANG Shao-ni;LIN Li-li(The Central Hospital of Chaozhou City,Chaozhou 521000,China)

机构地区：[1]广东省潮州市中心医院,广东潮州521000

出　　处：《云南中医中药杂志》2021年第7期29-32,共4页Yunnan Journal of Traditional Chinese Medicine and Materia Medica

基　　金：广东省中医药科研项目(20191407)。

摘　　要：目的观察加味桂枝加葛根汤治疗非特异性下腰痛(NLBP)寒湿证患者的临床疗效。方法将符合NLBP的120例患者,按随机原则分为治疗组60例与对照组60例。治疗组给予加味桂枝加葛根汤,对照组给予双氯芬酸钠缓释片,2组的疗程均为10 d,记录2组患者治疗前后及治疗后1个月、3个月的VAS评分、ODI评分、中医证候积分、疗效及复发率。结果治疗组治疗后、治疗后1个月、3个月的VAS评分、ODI评分、中医证候积分与治疗前比较,差异有统计学意义(P<0.05),治疗后VAS评分与对照组比较,差异无统计学意义(P>0.05),治疗后ODI、中医证后积分与对照组比较,差异有统计学意义(P<0.05);治疗后1个月、3个月,治疗组的VAS、ODI及中医证候积分与对照组比较,差异均有统计学意义(P<0.05)。治疗组临床疗效总有效率为95%,对照组83.3%,两者差异有统计学意义(P<0.05);随访3个月治疗组复发率21.7%,对照组复发率68.3%,差异有统计学意义(P<0.05)。结论加味桂枝加葛根汤治疗非特异性下腰痛疗效确切,远期疗效好,复发率低,值得临床进一步研究和推广。Objective:To observe the clinical effect of modified Cassia twig and Pueraria Decoction in the treatment of non-specific low back pain(NLBP)patients with cold-damp syndrome.Methods:120 patients who met NLBP criteria were randomly divided into a treatment group and a control group,60 cases per group.The treatment group was given modified Cassia twig and Pueraria Decoction and the control group was given diclofenac sodium sustained-release tablets.The two groups had a 10-day course of treatment.The VAS scores and ODI scores of the two groups were recorded before and after treatment and the TCM syndrome score,curative effect and recurrence rate after treatment and after 1-month and 3-month treatment were compared with those of the prior treatment.Results:The VAS score,ODI score,TCM syndrome score of the treatment group after treatment and after 1-month and 3-month treatment were compared with those of the prior treatment and the difference was statistically significant(P<0.05).The VAS score after treatment was compared with that of the control group and the difference was not statistically significant(P>0.05).After treatment,the ODI and TCM scores of the treatment group were compared with those of the control group,and the difference was statistically significant(P<0.05).After 1-month and 3-month treatment,the VAS,ODI and TCM syndrome scores of the treatment group were compared with those of the control group,and the difference was statistically significant(P<0.05).The total clinical effective rate of the treatment group was 95%and that of the control group was 83.3%,and the difference was statistically significant(P<0.05).The recurrence rate of the treatment group was 21.7%and the control group was 68.3%by a 3-month follow-up and the difference was statistically significant(P<0.05).Conclusion:Modified Cassia twig and Pueraria Decoction has a definite curative effect in the treatment of non-specific low back pain patients,with good long-term curative effect and low recurrence rate,and is worthy of further clinical r

关 键 词：加味桂枝加葛根汤 非特异性下腰痛 临床疗效 复发 

分 类 号：R681.5[医药卫生—骨科学]