Serotonylation: A novel histone H3 marker  

作　　者：Lin Fu Lingqiang Zhang 

机构地区：[1]Institute of Chronic Disease,Qingdao Municipal Hospital,Qingdao University,266000 Qingdao,China [2]State Key Laboratory of Proteomics,National Center of Protein Sciences(Beijing),Beijing Institute of Lifeomics,100850 Beijing,China

出　　处：《Signal Transduction and Targeted Therapy》2019年第1期548-549,共2页信号转导与靶向治疗（英文）

摘　　要：A recent study by Farrelly,L.A.et al.published in Nature showed that the serotonylation of glutamine at the Q5 site in histone H3 promotes the recruitment of TFIID in collaboration with adjacent H3K4 trimethylation 1.Protein posttranslational modifications(PTMs)of histones are associated with diverse biological processes through dynamically modulating chromatin structure and the transcriptional activity of genes 2.Epigenetic regulations are an integral part of brain functions ranging from the development of the nervous system beyond basic neurological functions to higher-order cognitive processes 3.

关 键 词：ROTON SYSTEM trimethyl 

分 类 号：O17[理学—数学]