2009-2019年菏泽市人间布鲁氏菌病监测分析  

Monitoring and Analysis of Brucellosis in Humans in Heze City from 2009 to 2019

作　　者：马永旭 王景花[3] 马敬仓[4] 徐凌忠[5] MA Yongxu;WANG Jinghua;MA Jingcang;XU Lingzhong(Caozhuang Township Health Center of Shanxian,Shanxian 274322,China;不详)

机构地区：[1]山东省单县曹庄乡卫生院,山东单县274322 [2]山东省单县疾病预防控制中心 [3]山东省东明县疾病预防控制中心 [4]山东省菏泽市疾病预防控制中心 [5]山东大学公共卫生学院

出　　处：《中国医学创新》2021年第18期85-89,共5页Medical Innovation of China

基　　金：国家自然科学基金委员会面上项目(71673169)。

摘　　要：目的:了解菏泽市人间布鲁氏菌病流行特征,为防控策略的制定提供科学依据。方法:收集2009-2019年中国疾病预防控制信息系统菏泽市传染病报告资料及菏泽市疾病预防控制中心实验室于2015年1月-2017年12月采集的2555例疑似布鲁氏菌病病例血清学资料检测结果。后续各年度检测工作按属地化管理要求,由各县区疾病预防控制中心自行完成。统计菏泽市不同县区、月份、性别、职业的人间布鲁病菌发病率。比较2015、2016、2017年的抗体阳性率。结果:2009-2019年菏泽市累计报告布鲁氏菌病2366例,年平均发病率为2.53/10万。2016年,在牡丹区出现1个暴发点,局部地区暴发流行。4~7月为发病高峰,四个月合计构成比为49.84%,2009-2019年菏泽市不同县区报告病例数构成比居前三位的县区分别为牡丹区、郓城县和曹县,构成比分别为25.95%、24.43%、16.74%。男女之比为2.45∶1,男性多于女性。≥25岁且<55岁,人间布鲁氏菌病例构成为66.95%。2366例中农民最多,为81.70%(1933/2366)。2015年1月-2017年12月,共检测2555例血清标本,布鲁氏菌抗体阳性率为24.31%(621/2555),2015、2016、2017年度抗体阳性率分别为21.01%(183/871)、25.11%(237/944)和27.16%(201/740),差异有统计学意义(χ^(2)=8.752,P<0.05)。结论:菏泽市布鲁氏菌病疫情有集中趋势,个别年度有疫情点。应重点加强重点人群的干预工作,并开展定期监测,落实好检疫制度等综合防控。Objective:To understand the epidemic characteristics of brucellosis in humans in Heze City and provide scientific basis for the formulation of prevention and control strategy.Method:The report data of infectious diseases in Heze,China Disease Control and Prevention Information System(CDS)from 2009 to 2019 were collected,and the serological data of 2555 suspected cases of brucellosis were collected from the laboratory of Heze Center for Disease Control and Prevention from January 2015 to December 2017,with subsequent annual testing being performed by the county and district centers for disease control and prevention according to localized management requirements.The incidences of Brucella in different counties,months,sexes and occupations in Heze City were analyzed.The antibody positive rates in 2015,2016 and 2017 were compared.Result:A total of 2366 cases of brucellosis from 2009 to 2019 were reported in Heze City,with an average annual incidence of 2.53/100000.In 2016,one outbreak spot appeared in Mudan District,and an epidemic occurred in local areas.The incidence peaked from April to July,and the total composition ratio of four months was 49.84%.The number of reported cases in different counties and districts of Heze City,the top three counties in terms of composition ratio were Mudan District,Yuncheng and Caoxian,with constituent ratios of 25.95%,24.43%and 16.74%,respectively.The male-to-female ratio was 2.45∶1,more male than females.Most of the cases were≥25 and<55 years old(66.95%).Among the 2366 cases,81.70%were farmers(1933/2366).From January 2015 to December 2017,a total of 2555 serum samples were detected,the positive rate of brucellosis antibodies was 24.31%(621/2555),and the positive rates of brucellosis antibodies in 2015,2016 and 2017 were 21.01%(183/871),25.11%(237/944)and 27.16%(201/740),respectively,the difference was statistically significant(χ^(2)=8.752,P<0.05).Conclusion:Brucellosis epidemic in Heze City has a central trend,with some epidemic points in individual years.We should focus on

关 键 词：人间布鲁氏菌病 细菌 防控措施 流行特征 

分 类 号：R516.7[医药卫生—内科学] R181.8[医药卫生—临床医学]