Multimodal epidermal devices for hydration monitoring  

作　　者：Siddharth Krishnan Yunzhou Shi R.Chad Webb Yinji Ma Philippe Bastien Kaitlyn E.Crawford Ao Wang Xue Feng Megan Manco Jonas Kurniawan Edward Tir Yonggang Huang Guive Balooch Rafal M.Pielak John A.Rogers 

机构地区：[1]Department of Materials Science and Engineering,Frederick Seitz Materials Research Laboratory,University of Illinois at Urbana-Champaign,Urbana,IL 61801,USA [2]Department of Materials Science and Engineering,Northwestern University,Evanston,IL 60208,USA [3]L’Oreal Tech Incubator,California Research Center,953 Indiana Street,San Francisco,CA 94107,USA [4]Department of Civil and Environmental Engineering,Mechanical Engineering,Materials Science and Engineering,Northwestern University,Evanston,IL 60208,USA [5]L’Oréal Research and Innovation,1 Avenue Eugène Schuller,Aulnay sous Bois 93601,France [6]Department of Engineering Mechanics,Center for Mechanics and Materials,Tsinghua University,Beijing 100084,China [7]L’Oréal Early Clinical,133 Terminal Avenue,Clark,NJ 07066,USA [8]Departments of Materials Science and Engineering,Biomedical Engineering,Chemistry,Mechanical Engineering,Electrical Engineering and Computer Science,and Neurological Surgery,Center for Bio-Integrated Electronics,Simpson Querrey Institute for Nano/biotechnology,Northwestern University,Evanston,IL 60208,USA

出　　处：《Microsystems & Nanoengineering》2017年第1期267-277,共11页微系统与纳米工程（英文）

基　　金：YM and XF acknowledge the support from the National Basic Research Program of China(Grant No.2015CB351900);National Natural Science Foundation of China(Grant Nos.11402135,11320101001);YH acknowledges the support from NSF(Grant Nos.DMR1121262,CMMI1300846,CMMI1400169,and CMMI1534120);the NIH(Grant No.R01EB019337);RCW acknowledges support from the National Science Foundation under grant no.DGE-1144245.

摘　　要：Precise,quantitative in vivo monitoring of hydration levels in the near surface regions of the skin can be useful in preventing skinbased pathologies,and regulating external appearance.Here we introduce multimodal sensors with important capabilities in this context,rendered in soft,ultrathin,‘skin-like’formats with numerous advantages over alternative technologies,including the ability to establish intimate,conformal contact without applied pressure,and to provide spatiotemporally resolved data on both electrical and thermal transport properties from sensitive regions of the skin.Systematic in vitro studies and computational models establish the underlying measurement principles and associated approaches for determination of temperature,thermal conductivity,thermal diffusivity,volumetric heat capacity,and electrical impedance using simple analysis algorithms.Clinical studies on 20 patients subjected to a variety of external stimuli validate the device operation and allow quantitative comparisons of measurement capabilities to those of existing state-of-the-art tools.

关 键 词：epidermal electronics hydration monitoring thermal characterization 

分 类 号：TG1[金属学及工艺—金属学]