Thermometry of photosensitive and optically induced electrokinetics chips  

作　　者：Feifei Wang Lianqing Liu Gongxin Li Pan Li Yangdong Wen Guanglie Zhang Yuechao Wang Gwo-Bin Lee Wen Jung Li 

机构地区：[1]State Key Laboratory of Robotics,Shenyang Institute of Automation,Chinese Academy of Sciences,110016 Shenyang,China [2]University of Chinese Academy of Sciences,100049 Beijing,China [3]Shenzhen Academy of Robotics,518057 Shenzhen,China [4]Key Laboratory of Advanced Process Control for Light Industry of the Ministry of Education,Institute of Automation,Jiangnan University,214122 Wuxi,China [5]Department of Power Mechanical Engineering,National Tsing Hua University,30013 Hsinchu,Taiwan [6]Department of Mechanical and Biomedical Engineering,City University of Hong Kong,Kowloon Tong,Hong Kong,China

出　　处：《Microsystems & Nanoengineering》2018年第1期190-198,共9页微系统与纳米工程（英文）

基　　金：This study was partially supported by the NSFC/RGC Joint Research Scheme(Project Nos.51461165501 and CityU132/14);the National Natural Science Foundation of China(Project Nos.61522312,61433017,and 61673278);the Shenzhen Science and Technology Innovation Commission Municipality(Project Nos.JCYJ20170818105431734 and JCYJ20150828104330541);the CAS FEA International Partnership Program for Creative Research Teams,and the Hong Kong Research Grants Council(Project Nos.CityU 116912,and 9041928).

摘　　要：Optically induced electrokinetics(OEK)-based technologies,which integrate the high-resolution dynamic addressability of optical tweezers and the high-throughput capability of electrokinetic forces,have been widely used to manipulate,assemble,and separate biological and non-biological entities in parallel on scales ranging from micrometers to nanometers.However,simultaneously introducing optical and electrical energy into an OEK chip may induce a problematic temperature increase,which poses the potential risk of exceeding physiological conditions and thus inducing variations in cell behavior or activity or even irreversible cell damage during bio-manipulation.Here,we systematically measure the temperature distribution and changes in an OEK chip arising from the projected images and applied alternating current(AC)voltage using an infrared camera.We have found that the average temperature of a projected area is influenced by the light color,total illumination area,ratio of lighted regions to the total controlled areas,and amplitude of the AC voltage.As an example,optically induced thermocapillary flow is triggered by the light image-induced temperature gradient on a photosensitive substrate to realize fluidic hydrogel patterning.Our studies show that the projected light pattern needs to be properly designed to satisfy specific application requirements,especially for applications related to cell manipulation and assembly.

关 键 词：EXCEEDING ILLUMINATION MANIPULATION 

分 类 号：TP3[自动化与计算机技术—计算机科学与技术]