二氧化碳激光联合中药坐浴治疗女性尖锐湿疣的疗效观察  

Observation on the effect of CO_(2) laser combined with traditional Chinese medicine sitz bath in the treatment of female condyloma acuminatum

作　　者：贾健 杨丹[1] JIA Jian;YANG Dan(Department of Obstetrics,Second Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine,Xianyang 712000,Shaanxi,China)

机构地区：[1]陕西中医药大学第二附属医院产一科,陕西咸阳712000

出　　处：《中国性科学》2021年第6期131-134,共4页Chinese Journal of Human Sexuality

摘　　要：目的探究二氧化碳(CO_(2))激光联合中药坐浴治疗女性尖锐湿疣的临床效果。方法选取2018年6月至2019年9月陕西中医药大学第二附属医院诊治的86例女性尖锐湿疣患者作为研究对象。依据随机数字表法分为研究组(n=43)和对照组(n=43)。对照组采用CO_(2)激光联合干扰素凝胶的治疗方案,研究组在对照组基础上加用中药坐浴。对两组临床治疗效、不良反应发生率、复发率及生活质量评分进行比较。结果研究组治愈率(62.79%)、总有效率(100.00%)均明显高于对照组(37.21%和86.04%),差异具有统计学意义(P<0.05);研究组与对照组不良反应发生率分别为6.98%、9.30%,差异无统计学意义(P>0.05);研究组的复发率(13.95%)明显低于对照组(48.84%),差异具有统计学意义(P<0.05);研究组生活质量总分及躯体健康、社会功能、心理健康、物质生活4个维度评分分别为(165.58±6.30)分、(87.90±7.93)分、(60.70±5.73)分、(50.12±4.49)分和(60.44±5.81)分,均明显高于对照组的(151.35±8.13)分、(65.98±5.64)分、(49.82±4.45)分、(38.78±3.10)分和(49.47±4.50)分,差异均具有统计学意义(P<0.05)。结论女性尖锐湿疣采用CO_(2)激光联合中药坐浴治疗,临床疗效显著,安全性高,复发率低,可明显提升生活质量,具有较高的临床应用价值。Objective To explore the clinical effect of CO_(2) laser combined with traditional Chinese medicine sitz bath in the treatment of female condyloma acuminatum. Methods 86 female patients with condyloma acuminatum diagnosed and treated in the Second Affiliated Hospital of Shaanxi University of Traditional Chinese Medicine from June 2018 to September 2019 were selected and divided into study group(n=43) and control group(n=43) according to random number table method. The control group was treated with CO_(2) laser combined with interferon gel, while the research group was additionalized with Chinese medicine sitz bath on the basis of the control group. Clinical efficacy, incidence of adverse reactions, recurrence rate and quality of life score were compared between the two groups. Results The cure rate(62.79%) and total effective rate(100.00%) in the study group were significantly higher than those in the control group(37.21% and 86.04%), and the difference was statistically significant(P<0.05). The incidence of adverse reactions in the study group and the control group was 6.98% and 9.30%, respectively, with no statistical significance(P>0.05). The recurrence rate of the study group(13.95%) was significantly lower than that of the control group(48.84%), and the difference was statistically significant(P<0.05). In the study group, the scores of total quality of life, physical health, social function, mental health and material life were(165.58±6.30),(87.90±7.93),(60.70±5.73),(50.12±4.49) and(60.44±5.81) points, respectively, significantly higher than those in the control group(151.35±8.13),(65.98±5.64),(49.82±4.45),(38.78±3.10) and(49.47±4.50), and the differences were statistically significant(P<0.05). Conclusions The treatment of female condyloma acuminatum with CO_(2) laser and traditional Chinese medicine sitz bath has significant clinical effect, high safety, low recurrence rate, and significant improvement of quality of life, so it has high clinical application value.

关 键 词：CO_(2)激光 中药坐浴 尖锐湿疣 干扰素 

分 类 号：R759[医药卫生—皮肤病学与性病学]