机构地区:[1]黑龙江中医药大学,黑龙江哈尔滨150040 [2]黑龙江省中医药科学院,黑龙江哈尔滨150001
出 处:《针灸临床杂志》2021年第7期15-20,共6页Journal of Clinical Acupuncture and Moxibustion
基 金:黑龙江省自然科学基金,编号:YQ2020H029;黑龙江省中医药管理局项目,编号:ZHY2020-163。
摘 要:目的:观察揿针结合于氏丛刺治疗卒中后抑郁的临床疗效。方法:将90例患者随机分为对照组30例、传统针刺组30例和联合针刺组30例。对照组在基础治疗基础上,予以口服舍曲林,传统针刺组在对照组基础上予以传统针刺干预,联合针刺组在对照组的基础上,予以揿针结合额区丛刺干预,3组均每日1次,每周7次,连续治疗6周。3组患者分别于治疗前和治疗6周时运用24项汉密尔顿抑郁量表(HAMD)、改良爱丁堡-斯堪的那维亚神经功能缺损评分量表(MESSS)以及测定5-HT水平比较3组间的疗效差异。结果:治疗后,3组患者HAMD评分和MESSS评分均较治疗前显著下降,差异具有统计学意义(P<0.01),传统针刺组和联合针刺组优于对照组,差异具有统计学意义(P<0.05或P<0.01)。治疗后3组患者5-HT水平较治疗前水平显著增高,差异具有统计学意义(P<0.01),传统针刺组和联合针刺组优于对照组,差异具有统计学意义(P<0.01)。疗效评定方面,对照组总有效率65.52%(19/29),传统针刺组和联合针刺组总有效率分别为78.57%(22/28)和89.66%(26/29)。结论:在舍曲林基础上揿针结合于氏丛刺或传统针刺治疗卒中后抑郁比单独应用舍曲林更为有效、安全。揿针联合于氏丛刺较传统针刺疗效更优,值得临床推广应用。Objective:To observe the clinical effect of thumbtack needling combined with YU’s clustering acupuncture in the treatment of post-stroke depression(PSD).Methods:90 patients were randomly divided into the control group(n=30),the traditional acupuncture group(n=30)and the combined acupuncture group(n=30).On the basis of basic treatment,the control group was treated with Sertraline;on the treatment basis of the control group,the traditional acupuncture group was treated with traditional acupuncture and the combined acupuncture group was treated with thumbtack needling combined with clustering acupuncture.The treatment was once a day,7 times a week for 6 weeks.The scores of 24-item Hamilton Depression Scale(HAMD)and modified Edinburgh-Scandinavian stroke scale(MESSS)and the level of 5-HT were observed and compared among the three groups before and after six weeks of the treatment.Results:The scores of HAMD and MESSS were significantly decreased after the treatment than those before the treatment in the three groups(P<0.01);the decreases in the traditional acupuncture group and the combined acupuncture group were more significant than those in the control group(P<0.05,P<0.01).The level of 5-HT was significantly increased after the treatment than that before the treatment in the three groups(P<0.01),and the increase in the traditional acupuncture group and the combined acupuncture group was more significant than that in the control group(P<0.01).In terms of the total effective effect,it was 65.52%(19/29)in the control group,78.57%(22/28)in the traditional acupuncture group and 89.66%(26/29)in the combined acupuncture group.Conclusion:The therapy of thumbtack needling combined with YU’s clustering acupuncture or the therapy of traditional acupuncture on the treatment basis of Sertraline is more effective and safer than the treatment of Sertraline alone in the treatment of PSD.Thumbtack needling combined with YU’s clustering acupuncture has better curative effect than the traditional acupuncture and is worthy of cl
分 类 号:R246.6[医药卫生—针灸推拿学]
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