心肌梗死后交感神经激活致室性心律失常机制的研究进展  

Research progress on the mechanism of ventricular arrhythmia caused by sympathetic nerve activation after myocardial infarction

作　　者：岳英芳(综述) 张瑞英(审校)[1] YUE Yingfang;ZHANG Ruiying(Department of Internal Medical Critical Care Unit,First Affiliated Hospital of Harbin Medical University,Harbin 150001,China)

机构地区：[1]哈尔滨医科大学附属第一医院内科危重症科,哈尔滨150001

出　　处：《临床与病理杂志》2021年第7期1685-1689,共5页Journal of Clinical and Pathological Research

基　　金：哈尔滨市科技创新人才基金(2017RAXXJ064)。

摘　　要：心肌梗死后室性心律失常是在临床病例中导致此种心脏病患者猝死的主要原因之一。因此,为降低猝死率,缺血诱导心律失常的病理机制引起广泛关注。交感神经过度激活促使神经对心肌活动支配的不均一性,导致心脏电传导紊乱,是心律失常发生和维持的重要机制,抑制交感神经过度激活可有效防止室性心律失常的发生。Ventricular arrhythmia after myocardial infarction is one of the main causes of sudden death in patients with this heart disease in clinical cases.Therefore,in-depth researches on the mechanism of ischemia-induced arrhythmia in order to reduce the rate of sudden death have attracted widespread attention.Excessive activation of sympathetic nerves leads to uneven innervation of the myocardium and further results in cardiac electrical conduction disorder,which present an important mechanism for the occurrence and maintenance of arrhythmia.Additionally,targetd intervention performed in them can effectively prevent the occurrence of ventricular arrhythmia.

关 键 词：心肌梗死 室性心律失常 交感神经激活 

分 类 号：R54[医药卫生—心血管疾病]