肾结石患者低柠檬酸尿症代谢相关危险因素分析  

Analysis of metabolism associated risk factors of hypocitrateuria in patients with kidney stone

作　　者：乔逸[1] 肖河[1] 樊晓红[2] 石冰冰[1] 纪志刚[1] QIAO Yi;XIAO He;FAN Xiao-hong;SHI Bing-bing;JI Zhi-gang(Department of Urology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China;Department of Nephrology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences &Peking Union Medical College, Beijing 100730, China)

机构地区：[1]中国医学科学院北京协和医学院北京协和医院泌尿外科,北京100730 [2]中国医学科学院北京协和医学院北京协和医院肾内科,北京100730

出　　处：《基础医学与临床》2021年第8期1177-1180,共4页Basic and Clinical Medicine

摘　　要：目的回顾性分析肾结石患者中低柠檬酸尿症的代谢相关危险因素。方法回顾性分析北京协和医院泌尿外科代谢评估数据库中2016年5月至2021年1月纳入的92例临床资料完整的肾结石患者情况,以低柠檬酸尿症为因变量,以性别、年龄和代谢异常因素,包括体质量指数、高血压、糖尿病、高脂血症及高尿酸血症为自变量,通过二元Logistic回归分析,评估低柠檬酸尿症的代谢相关危险因素。结果在肾结石患者中,高血压是低柠檬酸尿症的危险因素(OR=4.48,95%CI:1.58~12.70,P<0.01),其他各因素并未发现与低柠檬酸尿症明确相关。结论在肾结石患者中,高血压是低柠檬酸尿症的危险因素。Objective To retrospectively analyze metabolism associated risk factors of hypocitrateuria in kidney stone patients.Methods Totally 92 kidney stone patients with qualified data from metabolic evaluation database of Peking Union Medical College Hospital from May 2020 to January 2021 were included in this retrospective analysis.With hypocitrateuria as dependent variable,and gender,age and metabolic factors,including body mass index,hypertension,diabetes mellitus,hyperlipidemia and hyperuricemia,as independent variables,binary Logistic regression was used to analyze metabolism associated risk factors of hypocitraturia.Results In kidney stone patients,hypertension was risk factors of hypocitrateuria(OR=4.48,95%CI:1.58~12.70,P<0.05),and other factors were not found to be associated with hypocitrateuria.Conclusions In kidney stone patients,hypertension is a risk factor of hypocitrateuria.

关 键 词：肾结石 低柠檬酸尿症 代谢相关危险因素 

分 类 号：R691.4[医药卫生—泌尿科学]