检索规则说明:AND代表“并且”;OR代表“或者”;NOT代表“不包含”;(注意必须大写,运算符两边需空一格)
检 索 范 例 :范例一: (K=图书馆学 OR K=情报学) AND A=范并思 范例二:J=计算机应用与软件 AND (U=C++ OR U=Basic) NOT M=Visual
作 者:陈洁静[1] 郑祖芬[1] Chen Jiejing;Zheng Zufen(Department of Pediatrics,Sihui People's Hospital,Zhaoqing 526200)
出 处:《数理医药学杂志》2021年第8期1189-1191,共3页Journal of Mathematical Medicine
摘 要:目的:探讨帕拉米韦和炎琥宁加奥司他韦治疗流感病毒感染患儿的效果。方法:按照简单随机化法将某院2019年6月~2020年6月65例流感病毒感染患儿分为对照组和观察组,对照组35例给予炎琥宁加奥司他韦治疗,观察组30例给予帕拉米韦氯化钠注射液治疗,两组均连续治疗5~7d,对比两组临床疗效、治疗前后的免疫功能(血清IgA、IgG、IgM)及血清CRP、SAA、ICAM-1、IL-6水平变化。结果:观察组患者临床总有效率为96.67%,高于对照组的62.86%(P<0.05);与治疗前相比,治疗后两组患者的血清IgA、IgG、IgM水平均升高,观察组高于对照组(P<0.05);与治疗前相比,治疗后两组患者的血清CRP、SAA、ICAM-1、IL-6水平均降低,观察组低于对照组(P<0.05)。结论:帕拉米韦氯化钠注射液可有效缓解流感病毒感染患儿的临床症状,提高治疗效果,提高机体抵抗力,改善免疫功能,减轻机体的炎症反应。Objective:To investigate the effect of pramivir and Yanhuning combined with oseltamivir in the treatment of children with influenza virus infection.Methods:According to the simple randomized method,65 children with influenza virus infection in a hospital from June 2019 to June 2020 were divided into control group(35 cases,Yanhuning combined with oseltamivir)and observation group(30 cases,paramivir sodium chloride injection).Both groups were treated for 5-7 days.The clinical efficacy,immune function(serum IgA,IgG,IgM)and serum CRP,SAA,ICAM-1,IL-6 levels before and after treatment were compared between the two groups.Results:The total effective rate of the observation group was 96.67%,which was higher than 62.86%of the control group(P<0.05).Compared with before treatment,the serum IgA,IgG and IgM levels of the two groups were increased after treatment,and the observation group was higher than the control group(P<0.05).Compared with before treatment,the levels of serum CRP,SAA,ICAM-1 and IL-6 in the two groups were decreased after treatment,and those in the observation group were lower than those in the control group(P<0.05).Conclusion:Paremivir sodium chloride injection can effectively relieve the clinical symptoms of children with influenza virus infection,improve the therapeutic effect,improve the body resistance,improve the immune function,and reduce the body's inflammatory reaction.
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在载入数据...
正在链接到云南高校图书馆文献保障联盟下载...
云南高校图书馆联盟文献共享服务平台 版权所有©
您的IP:216.73.216.3