电极温度对极低出生体重儿经皮二氧化碳分压和氧分压监测的影响  

Effect of electrode temperature on measurements of transcutaneous carbon dioxide partial pressure and oxygen partial pressure in very low birth weight infants

作　　者：李炳辉 赵长亮 曹顺利[1] 耿红丽[1] 李晶晶 朱敏 牛世平 LI Bing-Hui;ZHAO Chang-Liang;CAO Shun-Li;GENG Hong-Li;LI Jing-Jing;ZHU Min;NIU Shi-Ping(Department of Neonatology,Zibo Maternal and Child Health Hospital,Zibo,Shandong 255000,China)

机构地区：[1]山东省淄博市妇幼保健院新生儿科,山东淄博255000

出　　处：《中国当代儿科杂志》2021年第8期809-813,共5页Chinese Journal of Contemporary Pediatrics

摘　　要：目的评估在低于临床常用的电极温度下进行经皮二氧化碳分压(transcutaneous carbondioxide partial pressure,TcPCO_(2))和经皮氧分压(transcutaneous oxygenpartialpressure,TcPO_(2))监测在极低出生体重儿应用中的准确性和安全性。方法对45名极低出生体重儿进行TcPCO_(2)和TcPO_(2)监测,每个研究对象同时放置两个经皮监测仪,其中一个电极温度设置并保持临床常用于新生儿监测的42℃(对照组),另一个电极温度依次设置为38℃、39℃、40℃和41℃(试验组),通过配对t检验对各组监测结果进行比较,并通过Pearson相关性分析法对试验组和对照组的监测结果进行相关性分析,以及对试验组的监测结果与动脉血气分析值进行相关性分析。结果在38℃、39℃、40℃和41℃各电极温度下的TcPCO_(2)与对照组比较差异均无统计学意义(P>0.05),且各电极温度(38~41℃)试验组的TcPCO_(2)与对照组TcPCO_(2)(r>0.9,P<0.05)及动脉血二氧化碳分压(r>0.8,P<0.05)均呈极强的正相关。在38℃、39℃、40℃和41℃各电极温度下的TcPO_(2)与对照组比较差异有统计学意义(P<0.05),但与对照组TcPO_(2)(r=0.493~0.574,P<0.05)及动脉血氧分压(r=0.324~0.399)均呈显著正相关(P<0.05)。在所有电极温度下经皮监测均未发生皮肤损伤。结论较低电极温度(38~41℃)可准确监测极低出生体重儿血二氧化碳分压,可以取代临床常用的42℃;对于血氧分压,较低电极温度经皮监测可能有助于了解其变化趋势。Objective To evaluate the accuracy and safety of measurements of transcutaneous carbon dioxide partial pressure(TcPCO_(2))and transcutaneous oxygen partial pressure(TcPO_(2))at electrode temperatures lower than the value used in clinical practice in very low birth weight infants.Methods A total of 45 very low birth weight infants were enrolled.TcPCO_(2) and TcPO_(2) measurements were performed in these infants.Two transcutaneous monitors were placed simultaneously for each subject.One electrode was set and maintained at 42℃used in clinical practice for neonates(control group),and the other was successively set at 38℃,39℃,40°C,and 41℃(experimental group).The paired t-test was used to compare the measurement results between the groups.A Pearson correlation analysis was used to analyze the correlation between the measurement results of the experimental group and control group,and between the measurement results of experimental group and arterial blood gas parameters.Results There was no significant difference in TcPCO_(2) between each experimental subgroup(38-41℃)and the control group.TcPCO_(2) in each experimental subgroup(38-41℃)was strongly positively correlated with TcPCO_(2) in the control group(r>0.9,P<0.05)and arterial carbon dioxide partial pressure(r>0.8,P<0.05).There were significant differences in TcPO_(2) between each experimental subgroup(38-41℃)and the control group(P<0.05),but TcPO_(2) in each experimental subgroup(38-41℃)was positively correlated with TcPO_(2) in the control group(r=0.493-0.574,P<0.05)and arterial oxygen partial pressure(r=0.324-0.399,P<0.05).No skin injury occurred during transcutaneous measurements at all electrode temperatures.Conclusions Lower electrode temperatures(38-41℃)can accurately measure blood carbon dioxide partial pressure in very low birth weight infants,and thus can be used to replace the electrode temperature of 42°C.Transcutaneous measurements at the lower electrode temperatures may be helpful for understanding the changing trend of blood oxygen

关 键 词：经皮监测 二氧化碳分压 氧分压 电极温度 极低出生体重儿 

分 类 号：R722.6[医药卫生—儿科]