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作 者:骆守真[1] 郑艳[1] 常诚[1] LUO Shouzhen;ZHENG Yan;CHANG Cheng(Jiangsu Provincial Hospital of Traditional Chinese Medicine,Nanjing 210029,China)
机构地区:[1]江苏省中医院,南京210029
出 处:《长春中医药大学学报》2021年第4期905-908,共4页Journal of Changchun University of Chinese Medicine
基 金:2019年度江苏省中医药科技发展计划人才项目(RC201901)。
摘 要:肠道菌群在血管性认知障碍的发生、发展中起到了重要作用。研究表明,通过调节肠道菌群可以改善痴呆症状。中医“脾胃”与肠道菌群在生理、病理上均相类似,从脾胃治疗痴呆已被证明有效。目前,中医药通过调节肠道菌群以防治痴呆的研究还处于初起阶段。本研究旨在以调节肠道微生态为靶点,探讨从脾胃论治血管性认知障碍的作用机制,为血管性认知障碍的治疗提供新的思路。Intestinal flora plays an important role in the occurrence and development of vascular cognitive impairment through the brain-gut axis.Studies have shown that the symptoms of dementia can be improved by regulating the intestinal flora.The spleen and stomach of Chinese medicine is similar in physiology and pathology to the intestinal flora,and treating dementia from the spleen and stomach has been proven effective.At present,the research of traditional Chinese medicine on the prevention and treatment of dementia by regulating the intestinal flora is still in its infancy.Viewing regulating the intestinal microecology as a target,this study aims to explore the mechanism of treating vascular cognitive impairment from the spleen and stomach,and to provide a new idea for it.
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