右美托咪定喷鼻对肱骨髁上骨折患儿七氟醚麻醉生命体征及苏醒期躁动的影响  

Effect of dexmedetomidine nasal spray on vital signs and restlessness during recovery from sevoflurane anesthesia in children with supracondylar fracture of humerus

作　　者：莫蓓[1] 何佩娟[2] MO Bei;HE Peijuan(Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine,Nanchang 330006,China;Jiangxi Provincial Chest Hospital,Nanchang 330000,China)

机构地区：[1]江西中医药大学附属医院,江西南昌330006 [2]江西省胸科医院,江西南昌330000

出　　处：《临床医药实践》2021年第7期495-498,共4页Proceeding of Clinical Medicine

摘　　要：目的:探讨右美托咪定喷鼻对肱骨髁上骨折患儿七氟醚麻醉生命体征及苏醒期躁动的影响。方法:选择2018年1月—2020年4月拟行手法复位内固定治疗的84例肱骨髁上骨折患儿,按随机数字表法分为对照组和观察组,每组42例。观察组在麻醉诱导前30 min使用右美托咪定喷鼻,对照组喷入等剂量生理盐水。对比两组右美托咪定使用前(t_(0))、给药后15 min(t_(1)),术毕(t_(2))、麻醉恢复时(t_(3))的心率、平均动脉压(MAP)、苏醒期躁动、麻醉及不良反应情况。结果:两组t_(0)和t_(1)时心率、MAP相比,差异无统计学意义(P>0.05),观察组t_(2)和t_(3)时心率、MAP低于对照组,差异有统计学意义(P<0.05);观察组拔管时间、苏醒时间短于对照组,苏醒期躁动、恶心、呕吐发生率低于对照组,差异有统计学意义(P<0.05)。结论:右美托咪定喷鼻能够维持肱骨髁上骨折患儿生命体征平稳,缩短拔管时间、苏醒时间,降低苏醒期躁动和不良反应发生率。Objective:To investigate the effect of dexmedetomidine nasal spray on the vital signs of sevoflurane anesthesia and restlessness during recovery in children with supracondylar fractures of the humerus.Methods:A total of 84 children with supracondylar fractures of the humerus who to be treated with manual reduction and internal fixation in hospital from January 2018 to April 2020 were selected as the research objects.They were divided into two groups according to a random number table,with 42 cases in each group.The test group was given dexmedetomidine nasal spray 30 minutes before induction of anesthesia,and the control group was sprayed with the same dose of normal saline.The heart rate,mean arterial pressure(MAP),anesthesia,restlessness during recovery,and adverse reactions were compared between the two groups.Results:There was no statistical difference in heart rate and MAP between the two groups at t_(0) and t_(1)(P>0.05).The heart rate and MAP at t_(2) and t_(3) in the test group were lower than those in the control group,and the difference was statistically significant(P<0.05).The extubation time and recovery time were shorter than those of the control group.The incidence of restlessness,nausea and vomiting during the recovery period was lower than that of the control group,and the difference was statistically significant(P<0.05).Conclusion:Dexmedetomidine nasal spray can maintain the vital signs of children with supracondylar fractures of the humerus,shorten the time of extubation and recovery,and reduce the incidence of restlessness and adverse reactions during the recovery period.

关 键 词：肱骨髁上骨折 右美托咪定 七氟醚 全身麻醉 生命体征 苏醒期躁动 

分 类 号：R614[医药卫生—麻醉学]