中国南方人群腹壁皮下脂肪厚度与心脏质量的相关性  

Correlation between Abdominal Wall Subcutaneous Fat Thickness and Heart Weight in Southern Chinese Population

作　　者：乐嘉诚 吴秋萍 周南 张凯[1] 郑大 吕国丽[3] 成建定[1] YUE Jia-cheng;WU Qiu-ping;ZHOU Nan;ZHANG Kai;ZHENG Da;LÜGuo-li;CHENG Jian-ding(Faculty of Forensic Medicine,Zhongshan School of Medicine,Sun Yat-sen University,Guangzhou 510080,China;Department of Toxicology,School of Public Health,Sun Yat-sen University,Guangzhou 510080,China;Guangzhou Forensic Science Institute,Guangzhou 510030,China)

机构地区：[1]中山大学中山医学院法医学系,广东广州510080 [2]中山大学公共卫生学院卫生毒理系,广东广州510080 [3]广州市刑事科学技术研究所,广东广州510030

出　　处：《法医学杂志》2021年第3期351-357,共7页Journal of Forensic Medicine

基　　金：国家自然科学基金资助项目(81920108021);广州市科技计划资助项目(2019030015)。

摘　　要：目的研究腹壁皮下脂肪厚度和心脏质量间的相关性,为寻找适用于我国尸体检验中心脏质量标准值预测方法提供参考。方法收集中山大学法医鉴定中心1998—2017年受理的法医病理学尸体检验案例,设置排除标准筛选出总案例组,并从总案例组中筛选出6个疾病组和正常组。采用秩和检验比较正常组与各疾病组的心脏质量以确定疾病对心脏质量的影响,同时分性别按年龄分层对总案例组与正常组中腹壁皮下脂肪厚度与心脏质量进行Spearman秩相关分析并得到相关系数(rs)。结果在总案例组中,男性在所有年龄段中腹壁皮下脂肪厚度与心脏质量之间存在相关性(P<0.05);女性在15~<20岁和50~<60岁两者的相关性无统计学意义(P>0.05),而在其他年龄段具有相关性(P<0.05)。在正常组中,男性15~<40岁rs为0.411,40~<60岁rs为0.541,≥60岁rs为0.683;女性15~<40岁rs为0.249,40~<60岁rs为0.317,≥60岁相关性无统计学意义(P>0.05)。结论在总人群和正常人群中,男性腹壁皮下脂肪和心脏质量之间均具有相关性,将腹壁皮下脂肪厚度纳入我国男性心脏质量标准值的预测具有一定的意义。Objective To study the correlation between the abdominal wall subcutaneous fat thickness and heart weight,so as to provide reference for prediction methods of normal range of heart weight that is suitable for autopsy in China.Methods The forensic pathology autopsy cases accepted by Center for Medicolegal Expertise of Sun Yat-sen University from 1998 to 2017 were collected.Then the exclusion criteria were determined,and according to them the total case group was selected,and the 6 disease groups and the normal group were further selected from the total case group.The rank sum test was used to compare the heart weight of the normal group and the disease groups to determine the influence of diseases on heart weight.Then the Spearman rank correlation analysis of abdominal wall subcutaneous fat thickness and heart weight in different genders and different ages in the total case group and the normal group was conducted to get the correlation coefficient(rs).Results In the total case group,correlation between abdominal wall subcutaneous fat thickness and heart weight was shown in males of all ages(P<0.05);while in females,the correlation had no statistical significance(P>0.05)in 15-<20 age and 50-<60 age,but was statistically significant(P<0.05)in other age groups.For the males in the normal group,rs was respectively 0.411,0.541 and 0.683 in the 15-<40 age,the 40-<60 age,and the≥60 age.For the females,rs was respectively 0.249 and 0.317 in the 15-<40 age and the 40-<60 age.The correlation in the≥60 age had no statistical significance(P>0.05).Conclusion In the general population and the normal population,abdominal wall subcutaneous fat thickness is correlated with the heart weight of males.It is of significance to include the abdominal wall subcutaneous fat thickness in the prediction of normal range of heart weight for males in China.

关 键 词：法医病理学 腹壁皮下脂肪 心脏质量 相关性分析 

分 类 号：DF795.1[医药卫生—法医学]