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作 者:Sergiy A.Gulyar Zynaida A.Tamarova
机构地区:[1]Department of Sensory Signaling,Bogomoletz Institute of Physiology,National Academy of Sciences of Ukraine,Kyiv 401601,Ukraine [2]International Medical Innovation Center Zepter,Kyiv 02152,Ukraine
出 处:《Journal of US-China Medical Science》2021年第1期1-19,共19页美中医学(英文版)
摘 要:We studied the dynamics of the tonic pain response(formalin test)and changes in the pain threshold to electrical stimulation(vocalization test on an electric platform)in animals depending on the polarization and wavelength range of light.The study was carried out on 280 adult white male mice weighing 28-33 g.Each experimental series consisted of 10 animals,a placebo series(control without light)-20 animals.It has been experimentally verified that when polychromatic polarized light(PL)is used,pain weakened statistically significant due to local reactions from the locus of pain and systemic processes through pain points of acupuncture(AP).We revealed that the factors that significantly enhance the analgesic result of polychromatic light therapy are the polarization of light and the long-wavelength part of visible light.When applying different wavelength ranges of PL to the AP E-36,it was noted that all seven colors of the spectrum,as well as polychromatic(white)light,effectively suppressed pain.Analgesia was 36.1-54.4%,and no differences in statistical significance were found between the reactions.When PL in the long-wavelength range(red,yellow,orange)was applied to the pain locus,the pain response was shortened by 50.1-64.1%,while the other colors(blue,green,purple)weakened pain only by 31.5-44.3%.The differences between them and the most effective red light are statistically significant.Red light was also more efficient than polychromatic PL,and no significant differences were found between red,orange and yellow colors.The possibility of AP response to each of the main monochromatic ranges of sunlight and obtaining reactions that can be used for medicinal purposes has been experimentally verified.Clinical observations of human pain have shown dynamics similar to those obtained in animals.The analgesia caused by red light reached 48.2%.The importance of using photobiomodulation in clinical and home conditions is emphasized.
关 键 词:PHOTOBIOMODULATION Bioptron polarized polychromatic light red light colour therapy ANALGESIA acute pain tonic pain AP points pain and non-pain behavioural reactions.
分 类 号:R24[医药卫生—中医临床基础]
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