支气管肺泡灌洗术联合布地奈德雾化溶液支气管内给药治疗儿童RMPP的效果  

Effect of bronchoalveolar lavage combined with intrabronchial administration of budesonide aerosol solution in treating child refractory Mycoplasma pneumoniae pneumonia

作　　者：宾松涛 王继 王霖[1] 李小娟[1] 王艳华[1] BIN Songtao;WANG Ji;WANG Lin;LI Xiaojuan;WANG Yanhua(Department of Respiratory Medicine,Kunming Municipal Children′s Hospital,Kunming,Yunnan 650000,China)

机构地区：[1]昆明市儿童医院呼吸内科,云南昆明650000

出　　处：《现代医药卫生》2021年第15期2565-2568,2572,共5页Journal of Modern Medicine & Health

基　　金：云南省昆明市SW(后备)千工程、局级后备人选培养人选项目[2021-SW(后备)-63]。

摘　　要：目的探讨支气管肺泡灌洗术联合布地奈德雾化溶液支气管内给药治疗儿童难治性肺炎支原体肺炎(RMPP)的临床疗效。方法采用前瞻性研究方法,选取2018年7月至2020年7月该院呼吸内科收治的需给予支气管肺泡灌洗治疗的RMPP患儿120例。采用随机数字表法分为对照组(53例)和治疗组(67例)。对照组给予常规肺泡灌洗治疗,治疗组给予肺泡灌洗术联合布地奈德雾化溶液支气管内给药治疗。比较2组患儿总有效率、住院时间、影像学吸收好转率及术后3 d咳嗽情况。结果2组患儿总有效率、影像学吸收好转率比较,差异均无统计学意义(P>0.05);治疗组患儿平均住院时间明显短于对照组,术后3 d咳嗽症状减轻程度明显优于对照组,差异均有统计学意义(P<0.05)。结论支气管肺泡灌洗术联合布地奈德雾化溶液支气管内给药治疗儿童RMPP可缩短住院时间,明显缓解术后咳嗽症状。Objective To explore the clinical effect of bronchoalveolar lavage combined with intrabronchial administration of budesonide aerosol solution in the treatment of child refractory Mycoplasma pneumoniae pneumonia(RMPP).Methods One hundred and twenty cases of RMPP requiring bronchoalveolar lavage in the respiratory department of this hospital from July 2018 to July 2020 were selected by using the prospective study method and divided into the control group(53 cases)and the treatment group(67 cases)according to the random number table method.The control group was given the routine alveolar lavage and the treatment group was given the bronchoalveolar lavage combined with intrabronchial administration of budesonide atomized solution.The total effective rate,hospitalization time,absorption and improvement rate in imaging and cough situation within postoperative 3 d were compared between the two groups.Results The total effective rate and absorption improvement rate in imageology had no statistical difference between the two groups(P>0.05);the average hospitalization time in the treatment group was significantly shorter than that in the control group,the relief degree of cough within postoperative 3 d in the treatment group was significantly superior to that in the control group,and the differences were statistically significant(P<0.05).Conclusion The bronchoalveolar lavage combined with intrabronchial administration of budesonide aerosol solution in treating child RMPP can shorten the hospitalization time and significantly relieve the cough symptoms.

关 键 词：支气管肺泡灌洗 肺炎 肺炎支原体 儿童 布地奈德 气雾剂 溶液 支气管镜 

分 类 号：R725.6[医药卫生—儿科] R459.1[医药卫生—临床医学]