湖北省2015-2019年HIV感染孕产妇特征及母婴阻断情况  

Characteristics of HIV-infected pregnant women and status quo of preventing mother-to-child transmission in Hubei from 2015 to 2019

作　　者：徐阳欢 张蕃[2] 戴琼[1] 王玉红[1] 尹丹丹 程凯 代国红[1] XU Yanghuan;ZHANG Fan;DAI Qiong;WANG Yuhong;YIN Dandan;CHENG Kai;DAI Guohong(Health Care Department,Maternal and Child Health Hospital of Hubei Province,Wuhan 430070,Hubei,China;Infectious Disease Prevention and Control Institute,Hubei Province Center for Disease Control and Prevention,Wuhan 430079,Hubei)

机构地区：[1]湖北省妇幼保健院,武汉430070 [2]湖北省疾病预防控制中心,武汉430079

出　　处：《中国艾滋病性病》2021年第7期699-702,共4页Chinese Journal of Aids & STD

摘　　要：目的分析湖北省2015-2019年孕产妇HIV感染的流行病学特征及母婴阻断情况,为制定预防和控制HIV母婴传播策略提供科学依据。方法对湖北省2015年1月至2019年12月在预防艾滋病、梅毒和乙肝母婴传播管理信息系统中上报的HIV阳性孕产妇病例进行回顾性研究,分析其特征和母婴阻断情况。结果2015-2019年湖北省孕产妇的HIV阳性检出率为1.28/万;孕产妇的HIV检测率呈逐年上升趋势(χ^(2)_(趋势)=6015.10,P<0.05),阳性检出率总体呈上升趋势(χ^(2)_(趋势)=9.633,P<0.05);382例HIV阳性孕产妇中,20~34岁占比80.37%(307例),汉族占比86.65%(331例),初中文化占比48.43%(185例),家务及待业占比40.05%(153例),本县区户籍人口占比80.37%(307例)。191例(50.00%)HIV阳性孕产妇感染途径为性传播,187例(48.95%)在孕期保健时被检出确认为感染者,259例(67.80%)在孕期接受预防母婴传播干预服务;HIV阳性孕产妇的分布呈现出地域差异,恩施州地区阳性检出率3.10/万(53/171071);245例HIV阳性产妇及所生儿童年度抗病毒用药率均>90%;2015-2019年湖北省HIV的母婴传播率在1.76%~5.27%之间波动。结论湖北省孕产妇HIV感染率处于较低水平,但艾滋病母婴传播率未达到国际消除HIV认证标准,建议今后的项目管理过程中,突出重点人群、重点市州,采取针对性的综合干预措施。Objective To analyze the epidemiological characteristics of HIV-infected pregnant women and the status of mother-to-child prevention in Hubei province from 2015 to 2019 to provide a scientific basis for formulating prevention and control strategies of mother-to-child transmission.Methods A retrospective study was conducted on HIV-infected maternal cases reported in the information system IPMTCT in Hubei province from January 2015 to December 2019.The characteristics and the status of prevention from mother-to-child HIV transmission were analyzed.Results The HIV positive detection rate of pregnant women was 1.28 per 10000 from 2015 to 2019.The maternal HIV testing rate in Hubei province was assumed year by year(χ^(2)=6015.10,P<0.05),and the positive rates of detection were on the rise in the past five years(χ^(2)=9.633,P<0.05).Of the 382 HIV-positive pregnant women(HIV-PPW),80.37%(307 cases)were aged between 20 and 34 years old,with Han nationality accounted for 86.65%(331 cases).Of those HIV-PPW,48.43%(185 patients)had junior middle school education,40.05%(153 cases)were housewives or unemployed,80.37%(307 cases)were with residents in the county.191(50.00%)PPW were infected sexually,and 187(48.95%)were tested HIV positive through a physical check program during pregnancy.259(67.80%)of the HIV-PPW received Mother-to-child transmission intervention services during pregnancy.The distribution of HIV-infected pregnant women showed regional differences,and it was 3.10 per 10,000(53/171071)in Enshi Prefecture.The annual rate of antiviral drugs for pregnant women and children was more than 90%.The average mother-to-child transmission rate fluctuated between 1.76%and 5.27%from 2015 to 2019.In Conclusion The infection rate of maternal AIDS was still at the overall low prevalence level.With the better implementation of preventing mother-to-child transmission program on AIDS from 2015 to 2019.However,it had not met the internationally set standard on HIV elimination,so it is suggested that items as the project management p

关 键 词：孕产妇 艾滋病病毒 流行特征 母婴传播 

分 类 号：R512.91[医药卫生—内科学] R373.9[医药卫生—临床医学]