非糖尿病孕妇妊娠晚期血脂水平与巨大儿的相关性分析  

Association of maternal serum lipids at late gestation with the risk of macrosomia in women without diabetes mellitus

作　　者：丁玉芹[1] 桑琳[1] DING Yu-qin;SANG Lin(Department of Obstetrics and Gynecology,the Second People's Hospital of Hefei,Hefei 230011,China)

机构地区：[1]合肥市第二人民医院妇产科,安徽合肥230011

出　　处：《吉林医学》2021年第8期1806-1808,共3页Jilin Medical Journal

摘　　要：目的:探讨非糖尿病孕妇妊娠晚期血脂水平与巨大儿的相关关系。方法:选取非糖尿病性观察孕妇100例作为观察组,同时随机选择同期正常体重儿孕妇100例作为对照组,回顾性比较两组临床资料,Logistic回归分析巨大儿的风险因素。结果:妊娠晚期母体血清三酰甘油(TG)浓度高和高密度脂蛋白胆固醇(HDL-C)水平低与非糖尿病孕妇巨大儿风险增加相关,巨大儿的风险随着TG每增加1 mmol/L约增加1.059倍,而随HDL-C增加1 mmol/L,风险减少16%。结论:非糖尿病孕妇脂质代谢在胎儿过度生长中的具有重要作用,孕期定期检测血脂水平,合理控制血脂增长,对巨大儿的预防有重要临床意义。Objective To explore the relationship between blood lipid level and macrosomia in women without diabetes mellitus at late pregnancy.Method 100 cases of non-diabetic macrosomia in our hospital were selected as the observation group,and 100 cases of normal weight infants were randomly selected as the control group.The clinical data of the two groups were retrospectively compared,and the risk factors of macrosomia were analyzed by logistic regression.Results High serum triglyceride(TG)and low high-density lipoprotein cholesterol(HDL-C)levels were associated with an increased risk of macrosomia in non-diabetic pregnant women.The risk of macrosomia increased by 1.059-fold with every 1 mmol/L increase of TG,and 16%decrease with 1 mmol/L increase of HDL-C.Conclusion Lipid metabolism of non-diabetic pregnant women plays an important role in fetal overgrowth.Regular detection of blood lipid level during pregnancy and reasonable control of blood lipid growth have important clinical significance for the prevention of macrosomia.

关 键 词：巨大儿 非糖尿病性 血脂 

分 类 号：R714.5[医药卫生—妇产科学]