可溶性微针的应用研究进展  

Research progress in applications of dissolving microneedles

作　　者：杨忍忍 赵昕雨 姚站馨 王玖[1] 郭长江 高蔚娜 YANG Ren-ren;ZHAO Xin-yu;YAO Zhan-xin;WANG Jiu;GUO Chang-jiang;GAO Wei-na(Binzhou Medical College,Yantai,Shandong 264600,China;Institute of Environmental and Operational Medicine,Academy of Military Medical Sciences,Academy of Military Sciences,Tianjin 300050,China)

机构地区：[1]滨州医学院,山东烟台264600 [2]军事科学院军事医学研究院环境医学与作业医学研究所,天津300050

出　　处：《军事医学》2021年第6期454-458,F0003,共6页Military Medical Sciences

基　　金：国防科技创新特区项目(2018-2021);全军后勤科研计划(CWS14C074)。

摘　　要：可溶性微针是微针中的一大类,具有给药部位精确、药物渗透输送速度快、无需冷藏、运输便捷等特点,相对于传统的皮下注射方式优势明显。该文综述了可溶性微针的制备技术及其携带疫苗、激素、降糖药和麻醉剂等应用情况,旨在为研究者制备和应用可溶性微针提供借鉴和参考。The dissolving microneedle is one of the major types of microneedles.It combines the advantages of transdermal patches and is characterized by accurate delivery and fast delivery.Therefore,it has obvious advantages over traditional subcutaneous injections.In this paper,the preparation technology of dissolving microneedles is summarized,and their applications in carrying vaccines,hormone,hypoglycemic drugs,and anesthetics are reviewed in the hope of providing reference for preparation and application of dissolving microneedles.

关 键 词：可溶性微针 疫苗 应用 

分 类 号：K944[历史地理—人文地理学]