针刺蝶腭神经节对222例变应性鼻炎患者症状改善的临床观察  

Clinical observation of the improving effects of acupuncture at sphenopa-latine ganglia on different symptoms of 222 patients with allergic rhinitis

作　　者：张鹏[1] 商晓娟[1] 谭翊[1] 杨静[1] 王奎吉[2] 许世闻 汪芗 孙三峰 於堃[6] 赵新雨[7] 舒凝 杨威[1] 陈陆泉[1] Zhang Peng;Shang Xiaojuan;Tan Yi;Yang Jing;Wang Kuiji;Xu Shiwen;Wang Xiang;Sun Sanfeng;Yu Kun;Zhao Xinyu;Shu Ning;Yang Wei;Chen Luquan(Department of Acupuncture and Moxibustion,Beijing Tongren Hospital,Capital Medical University,Beijing 100010,China;Department of Otolaryngology,Head and Neck Surgery,Beijing Tongren Hospital,Capital Medical University,Beijing 100010,China;Department of Acupuncture and Moxibustion,Beijing Chinese Medicine Hospital Pinggu Hospital,Beijing 101200,China;Department of Acupuncture and Moxibustion,Beijing Tongzhou District Integrated Chinese and Western Medicine Hospital,Beijing 101100,China;Department of Acupuncture and Moxibustion,Beijing Huairou Hospital of Traditional Chinese Medicine,Beijing 101400,China;Yuetan Community Health Service Centre of Fuxing Hospital,Capital Medical University,Beijing 100045,China;Department of Acupuncture and Moxihustion,Beijing Chaovang District Traditional Chinese Medicinr Hospital,Beijing 100020,China;Department of Acupuncture and Moxibustion.Beijing Huian TCM Integrated Hospital,Beijing 100067,China)

机构地区：[1]首都医科大学附属北京同仁医院针灸科,北京100010 [2]首都医科大学附属北京同仁医院耳鼻喉头颈外科,北京100010 [3]北京市平谷区中医医院针灸科 [4]北京市通州区中西医结合医院针灸科 [5]北京市怀柔区中医医院康复科 [6]首都医科大学附属复兴医院月坛社区卫生服务中心 [7]北京市朝阳区中医医院针灸科 [8]北京汇安中西医结合医院针灸科

出　　处：《北京中医药大学学报》2021年第6期569-576,共8页Journal of Beijing University of Traditional Chinese Medicine

基　　金：北京市自然科学基金项目(No.7212166);首都卫生发展基金自主创新课题(No.2020-2-2055);北京市卫健委适宜技术推广项目(No.BHTPP202032);北京市中医药科技发展资金项目(No.JJ-2020-18);首都医科大学科研培育基金项目(No.PYZ20101)。

摘　　要：目的对针刺蝶腭神经节治疗变应性鼻炎患者多中心无对照研究资料中相关症状改善的程度、时间、持续性进行观察,分析该针刺法对变应性鼻炎的疗效。方法2017年4月—2018年6月在北京地区7个分中心对变应性鼻炎患者进行针刺蝶腭神经节治疗(每周2次,共4周),共纳入符合标准患者222例;在治疗前(第0周),治疗第2、3、4周(第2、3、4周)及随访(第8周)共5个时点记录患者的鼻炎症状量表(TNSS)中鼻塞、流涕、鼻痒、喷嚏4个主要症状不同程度例数和鼻炎伴随症状量表(TNNSS)中鼻涕从咽部流过、流泪、鼻或眼部瘙痒、鼻或口腔上颌疼痛、头痛5个伴随症状例数。比较主要症状及伴随症状分布的变化情况,以随访结束时较治疗前症状是否缓解、消失或不变、加重的例数为依据,比较针刺蝶腭神经节对诸症状疗效的差别。结果治疗前后,鼻塞、流涕、鼻痒、喷嚏症状分数总体分布差异具有统计学意义(P<0.05),且每2个相邻时点比较,后一时点症状更轻(P<0.01);伴随症状中鼻涕从咽部流过、流泪、鼻或眼部瘙痒、鼻或口腔上颌疼痛、头痛症状分数总体分布差异具有统计学意义(P<0.05),其中鼻涕从咽部流过、流泪、鼻或眼部瘙痒、鼻或口腔上颌疼痛后一时点较相邻的前一时点均症状减轻(P<0.01)。结论针刺蝶腭神经节可减轻变应性鼻炎主要症状及伴随症状,疗效确切;而以喷嚏、鼻塞、流涕、鼻痒为主要临床表现的变应性鼻炎患者采用针刺蝶腭神经节治疗可能获得较满意疗效。Objective To observe the differences in the improvement degree,speed and persistence of different symptoms in the treatment of allergic rhinitis(AR)with acupuncture at sphenopalatine ganglion in a multicenter,noncontrolled study,and analyze the effects of the acupuncture therapy on AR symptoms.Methods The clinical data were collected of 222 cases of AR patients treated with acupuncture at sphenopalatine ganglion from April 2017 to June 2018 twice a week for four weeks in seven centers in Beijing.At 5 time points,i.e.before treatment(Week 0),the 2 nd,3 rd,and 4 th week during treatment(Week 2,Week 3,and Week 4)and during the follow-up(Week 8),the numbers of cases with different degrees of the four main symptoms including nasal congestion,runny nose,itching nose and sneezing selected from Total Nasal Symptom Score(TNSS)were recorded and the numbers of cases with and without the five accompanying symptoms including nasal discharge flowing through the pharynx,tears,itching nose or eyes,nasal or oral maxillary pain and headache selected from Total Nonnasal Symptom Score(TNNSS)were also recorded.Non-parametric tests of score data were performed on the distribution of cases at different time points to compare the changes in the distribution of the main symptoms and accompanying symptoms.The effects of acupuncture at sphenopalatine ganglion were compared on the basis of the numbers of patients whose symptoms were relieved,eliminated,unchanged and aggravated at the end of the follow-up compared with those before treatment.Results Before and after treatment,there were statistically significant differences in the overall distribution of symptom scores of nasal congestion,runny nose,itching nose and sneezing(P<0.05).In addition,the symptoms were milder at the later time point between every two adjacent time points(P<0.01).There were also statistically significant differences in the overall distribution of symptom scores of nasal discharge flowing through the pharynx,tears,itching nose or eyes,nasal or oral maxillary pain and

关 键 词：蝶腭神经节 针刺技术 变应性鼻炎 多中心研究 得气 

分 类 号：R276.1[医药卫生—中医五官科学]