血小板制剂的非输注性临床应用刍议  

Discussion on the clinical non-transfusion application of platelet concentrates

作　　者：宫济武[1] 赵树铭 GONG Jiwu;ZHAO Shuming(Department of Blood Transfusion,Beijing Hospital y Beijing 100730,China;Guiqian International General Hospital.)

机构地区：[1]北京医院输血科,北京100730 [2]贵黔国际总医院

出　　处：《中国输血杂志》2021年第7期683-684,共2页Chinese Journal of Blood Transfusion

摘　　要：血小板制剂在患者止血及维护血管完整性方面具有重要作用,常常用于血小板减少症和血小板功能障碍患者的治疗性或预防性输注;近年来研究发现血小板还具有抗炎和促进组织修复等作用。血小板含有多种组织生长因子,因而能促进细胞与组织的生长与修复,促进伤口愈合等。目前自体富血小板血浆及血小板胶也广泛应用于临床患者的治疗,今后还可开展异体血小板,如异体富血小板血浆、血小板胶、冻干血小板等的非输注性临床治疗应用。Platelets concentrates play a vital role in the maintenance of normal hemostatic activity and the integrity of blood vessel wall.Accordingly,for patients with low platelet counts(thrombocytopenia)or dysfunction,platelet transfusion can be of significant value in preventing and treating hemorrhage.In recent years,various studies have proved that platelets also play a very important role on anti-inflammation and improvement of cell and tissue growth and repair in regeneration processes.Platelets with the natural source of various growth factors can help in wound healing and proliferation.At present,autologous platelet-rich plasma and platelet gel are also widely used in the treatment of clinical patients.Therefore,the non-transfusion therapy of allogeneic platelet concentrate and alternatives such as platelet rich plasma,platelet gel and dry platelet(freeze-dried platelet)should be applied on patients in the near future.

关 键 词：血小板 非输注性治疗 异体血小板 输血 

分 类 号：R457.1[医药卫生—治疗学] R331.143[医药卫生—临床医学]