异体血小板胶用于巨大主动脉瘤手术辅助治疗1例  

Application of allogeneic platelet gel in surgical operation for giant aortic aneurysms, one case

作　　者：吴建君 蒋彬 向仁雪 史荣辉 杨康 刘巍[3] 崔欣[3] 赵树铭 WU Jianjun;JIANG Bin;XIANG Renxue;SHI Ronghui;YANG Kang;LIU Wei;CUI Xin;ZHAO Shuming(Blood Transfusion,GuiQian International General Hospitaly Guiyang 550018,China;Car-diothoracic Surgery,GuiQian International General Hospitaly Guiyang 550018,China;Guizhou Province Blood Center)

机构地区：[1]贵黔国际总医院输血科,贵阳贵州550018 [2]贵黔国际总医院胸心外科,贵阳贵州550018 [3]贵州省血液中心,贵阳贵州550018

出　　处：《中国输血杂志》2021年第7期698-701,共4页Chinese Journal of Blood Transfusion

摘　　要：目的探讨异体血小板用于巨大主动脉瘤患者手术时血管吻合处及创面止血与修复的效果。方法 2020年8月将1个治疗剂量的异体血小板制备为血小板胶(PG,约220 mL)用于巨大主动脉瘤手术时血管吻合处及胸腔创面的喷洒和涂抹。结果患者手术时,经PG喷洒和涂抹后血管吻合部及创面约30 s即可见胶状物形成,止血效果良好,术后心包和纵膈引流液较少,ICU住院时间4 d。结论异体血小板可作为PRP制备为PG用于大手术时血管壁缝合及创面止血。Objective To explore the effect of allogeneic platelet gel on hemostasis and repair of vascular anastomoses and wounds in patients with giant aortic aneurysms during surgery.Methods One adult dose of allogeneic platelets,applied as platelet rich plasma(PRP),was prepared as platelet gel(PG)(about 220 mL)for spraying or smearing at the vascular anastomosis and thoracic wound during the surgery of giant aortic aneurysms.Results The gel formation was presented about 30 seconds after spraying or smearing with PG on the anastomotic and wound surface.The hemostatic effect is good,with less postoperative drainage fluid from pericardium and mediastinum than usual,and the ICU stay was 4 days.Conclusion Allogeneic platelets as a source of PRP to prepare PG may be applied to obtain the clotting and healing during surgical operation.

关 键 词：异体血小板 富血小板血浆 血小板胶 动脉瘤 

分 类 号：R543.16[医药卫生—心血管疾病] R457.1[医药卫生—内科学]