302例登革热心电图特征研究  

Study of characteristics of electrocardiogram in 302 patients with dengue

作　　者：杜谕君 陈莉 冯晓霞 韩焕钦 Du Yujun;Chen Li;Feng Xiaoxia;Han Huanqin(Department of Electrocardiogram,Affiliated Hospital of Guangdong Medical University,Zhanjiang 524001,China)

机构地区：[1]广东医科大学附属医院心电图室,湛江524001 [2]广东医科大学附属医院感染内科,湛江524001

出　　处：《新医学》2021年第8期599-602,共4页Journal of New Medicine

基　　金：国家自然科学基金(81471530);广东省湛江市科技攻关项目(2020B01105)。

摘　　要：目的分析登革热患者心电图的特征。方法回顾性分析302例登革热患者(登革热组)和同期300名健康体检者(对照组)的临床资料,对比2组心电图异常情况;进一步分析异常心电图治疗前后的变化及其特点。结果登革热组存在心电图异常的患者比例(51.32%,155/302)高于对照组(31.00%,93/300)(P<0.001);登革热组心电图异常发生频率高于对照组的有ST-T改变(27.81%,84/302)、窦性心动过缓(11.92%,36/302)(P均<0.05);有46例心电图异常的患者治疗后复查了心电图,其中窦性心动过缓发生频率较治疗前下降,差异有统计学意义(P<0.05);窦性心动过缓的患者共36例,16例(44.44%)合并ST-T改变,高于无窦性心动过缓的患者(25.56%,68/266),差异有统计学意义(P<0.05)。结论登革热患者心电图异常较普遍,主要表现为ST-T改变、窦性心动过缓;窦性心动过缓是登革热最常见的心律失常和较显著的心电图特征,可能有助于诊断登革热。Objective To analyze the characteristics of the electrocardiogram(ECG)in patients with dengue.Methods Clinical data of 302 cases of dengue(dengue group)and 300 healthy subjects(control group)during the same period were retrospectively analyzed.The abnormalities of ECG were statistically compared between two groups.The changes and abnormalities of ECG before and after treatment were subsequently analyzed.Results The proportion of patients with abnormal ECG in the dengue group was 51.32%(155/302),significantly higher than 31.00%(93/300)in the control group(P<0.001).In the dengue group,the frequency of abnormal ECG in terms of ST-T changes(27.81%,84/302)and sinus bradycardia(11.92%,36/302)was significantly higher than that in the control group(both P<0.05).Fortysix patients with abnormal ECG were reexamined by ECG after corresponding treatment.Among them,the frequency of sinus bradycardia was remarkably decreased compared with that before treatment(P<0.05).Among 36 dengue patients with sinus bradycardia,16 cases(44.44%)had ST-T changes,and the proportion was significantly higher than 25.56%(68/266)of their counterparts without sinus bradycardia(P<0.05).Conclusions ECG abnormalities are commonly observed in dengue patients,mainly manifested as ST-T changes and sinus bradycardia.Sinus bradycardia is the most common arrhythmia of dengue and a relatively prominent ECG feature,which may have certain hints for the clinical diagnosis of dengue.

关 键 词：登革热 心电图 窦性心动过缓 心律失常 诊断 

分 类 号：R512.8[医药卫生—内科学]