基于多层螺旋CT灌注成像评估胃癌患者血流动力学改变及其与临床病理参数的关系  

Evaluation on Hemodynamic Changes in Gastric Cancer Patients by Perfusion Imaging based on Multi-slice Spiral CT and Their Relationship with Clinicopath-ological Parameters

作　　者：常宝[1] 马发鹏[1] 任伟[1] CHANG Bao;MA Fa-peng;REN Wei(Department of Radiology,Jiaozuo Second People's Hospital,Jiaozuo 454001,Henan Province,China)

机构地区：[1]焦作市第二人民医院放射科,河南焦作454001

出　　处：《中国CT和MRI杂志》2021年第9期119-121,共3页Chinese Journal of CT and MRI

摘　　要：目的基于多层螺旋CT(MSCT)灌注成像评估胃癌患者血流动力学改变及其与临床病理参数的关系。方法收集2016年8月至2019年8月期间于我院行MSCT灌注成像检查的162例胃癌患者的临床影像资料,分析灌注参数血流量(BF)、血容量(BV)、平均通过时间(MTT)、表面通透性(PS)与患者临床病理参数的关系。结果低分化患者PS值显著高于中高分化患者,淋巴结转移患者PS值显著高于淋巴结未转移患者,远处转移患者PS值显著高于远处未转移患者,差异均有统计学意义(P<0.05);Ⅰ期患者BF、BV、MTT值<Ⅱ~Ⅲa期<Ⅲb~Ⅳ期(P<0.05);不同胃癌生长部位患者之间BF、BV、MTT、PS值比较,差异均无统计学意义(P>0.05)。结论MSCT灌注成像可准确反映胃癌患者血流动力学改变,评价组织、器官血流状态,多角度观察血管与肿瘤之间的关系,指导胃癌患者的术前评价。Objective To evaluate hemodynamic changes in gastric cancer patients by perfusion imaging based on multi-slice spiral CT(MSCT)and their relationship with clinicopathological parameters.Methods The clinical imaging data of 162 patients with gastric cancer who underwent MSCT perfusion imaging in the hospital from August 2016 to August 2019 were collected.The relationship between perfusion parameters[blood flow(BF),blood volume(BV),mean transit time(MTT),permeability surface(PS)],and clinical-pathological parameters of patients were analyzed.Results PS value of patients with poor differentiation was significantly higher than that with moderate and high differentiation.PS value of patients with lymph node metastasis was significantly higher than that without lymph node metastasis.PS value of patients with distant metastasis was significantly higher than that without distant metastasis(P<0.05).Arranging BF,BV,and MTT from low to high,the corresponding order was stageⅠpatients,Ⅱ-Ⅲa stage,andⅢb-IV stages(P<0.05).There was no significant difference in BF,BV,MTT,or PS among patients with gastric cancer at different growth sites(P>0.05).Conclusion MSCT perfusion imaging can accurately reflect hemodynamic changes of gastric cancer patients,evaluate the blood flow status of tissues and organs,observe the relationship between blood vessels and tumors from multiple angles,and guide the preoperative evaluation of gastric cancer patients.

关 键 词：多层螺旋CT 灌注成像 胃癌 血流动力学改变 临床病理参数 

分 类 号：R445.3[医药卫生—影像医学与核医学] R735.2[医药卫生—诊断学]