含两个手性中心的三唑类杀菌剂色谱分离研究进展  

Research progress in chromatographic separation of triazole fungicides containing two chiral centers

作　　者：唐守英 王飞 孟秀柔 张钰萍 TANG Shouying;WANG Fei;MENG Xiurou;ZHANG Yuping(Guizhou University Fine Chemical Research and Development Center,State Key Laboratory of Green Pesticides and Agricultural Biotechnology,Key Laboratory of Green Pesticide and Biological Engineering,Ministry of Education,Guiyang 550025,China)

机构地区：[1]贵州大学精细化工研究开发中心,绿色农药与农业生物工程国家重点实验室,教育部绿色农药与生物工程重点实验室,贵阳550025

出　　处：《农药学学报》2021年第4期617-627,共11页Chinese Journal of Pesticide Science

基　　金：国家重点研发计划子课题(2016YFD0200206-3);国家自然科学基金(21866009,21667007)。

摘　　要：三唑类杀菌剂是目前世界上广泛应用的杀菌剂,而绝大多数三唑类杀菌剂属于手性农药,具有1个或2个手性中心,存在2个或4个对映异构体。本文在近年有关三唑类杀菌剂研究成果的基础上,综述了采用高效液相色谱、超临界流体色谱、毛细管电泳、气相色谱和合相色谱法等方法对含两个手性中心的11种三唑类杀菌剂(氟环唑、多效唑、三唑醇、联苯三唑醇、丙环唑、苯醚甲环唑、叶菌唑、苄氯三唑醇、环唑醇、糠菌唑和乙环唑)进行分离测定的研究进展,可为多个手性中心三唑类化合物的分离、分析和深入研究提供参考。Triazole fungicides are widely used fungicides in the world.The vast majority of triazole fungicides are chiral pesticides with one or two chiral centers and two or four enantiomers.Based on the research results of triazole fungicides in recent years,this article summarized the chromatographic methods such as high performance liquid chromatography,supercritical fluid chromatography,capillary electrophoresis,gas chromatography,and convergence chromatography for the chiral analysis of 11 triazole fungicides with two chiral centers including epoxiconazole,paclobutrazol,triadimenol,bitertanol,propiconazole,difenoconazole,metconazole,diclobutrazol,cyproconazole,bromuconazole,and etaconazole.The research progress in the separation and determination of triazoles with different chiral centers can provide references for the separation,analysis,and in-depth study of triazole compounds with multiple chiral centers.

关 键 词：手性农药 多手性中心 三唑类杀菌剂 色谱分离 研究进展 

分 类 号：S482.2[农业科学—农药学] TQ450.2[农业科学—植物保护]