Rapid and simple analysis of amphetamine-type illegal drugs using excitation–emission matrix fluorescence coupled with parallel factor analysis  

作　　者：Buyi Xu Yi Ye Linchuan Liao 

机构地区：[1]Sichuan Provincial Department of Public Security,Chengdu,China [2]Department of Forensic Toxicological Analysis,West China School of Preclinical and Forensic Medicine,Sichuan University,Chengdu,China

出　　处：《Forensic Sciences Research》2019年第2期179-187,共9页法庭科学研究（英文）

基　　金：supported by National Natural Science Foundation of China[grant number 81373239].

摘　　要：Nowadays,the abuse of illegal drugs has been an increasingly grim problem in the world.Excitation–emission matrix fluorescence combined with parallel factor analysis was used to make a quantitative analysis of the simulated amphetamine-type illegal drugs.Satisfactory results were achieved for simultaneous determination of methamphetamine(MAM)and 3,4-methylenedioxymethamphetamine(MDMA)in the presence of adulterants.The average recoveries were(99.8±0.6)%and(101.6±5.7)%for MAM and MDMA,respectively.Figures of merit including root-mean-square error of calibration and prediction,sensitivity and selectivity were investigated to evaluate the performance of the proposed method.The limits of detection were 0.054 and 0.0021 g/mL for MAM and MDMA,respectively.

关 键 词：Forensic science illegal drugs excitation–emission matrix fluorescence PARAFAC 

分 类 号：D91[政治法律—法学]