卒中发病前高血压控制情况与缺血性脑卒中分型的相关性分析  

Correlation between premorbid hypertension control and the classification of ischemic stroke

作　　者：曹琴琴 蒋蔚 华烨 蒋思明 马涛[1] CAO Qinqin;JIANG Wei;HUA Ye;JIANG Siming;MA Tao(Department of Neurology,Wuxi Clinical College of Nantong University,Wuxi City Second People′s Hospital of Jiangsu Province,Wuxi,Jiangsu,214002)

机构地区：[1]南通大学无锡临床学院/江苏省无锡市第二人民医院神经内科,江苏无锡214002

出　　处：《实用临床医药杂志》2021年第11期39-42,共4页Journal of Clinical Medicine in Practice

基　　金：江苏省青年医学人才(QNRC2016145);南通大学临床研究专项青年项目(2019LQ024)。

摘　　要：目的探讨缺血性脑卒中合并高血压患者发病前高血压治疗控制情况与缺血性脑卒中分型之间的关系。方法回顾性分析681例大动脉粥样硬化(LAA)型或小血管闭塞(SVO)型缺血性脑卒中合并高血压患者的临床资料,采用多因素Logistic回归分析法分析卒中发病前高血压控制情况与LAA型缺血性脑卒中之间的关系。结果卒中发病前高血压未控制患者(OR=1.607,95%CI为1.102~2.343)发生LAA型缺血性脑卒中的可能性更大。超重(OR=1.498,95%CI为1.066~2.105)、糖尿病(OR=1.803,95%CI为1.215~2.674)、男性(OR=1.804,95%CI为1.190~2.733)患者发生LAA型缺血性脑卒中的可能性更大。结论规范化治疗并控制高血压可能会降低LAA型缺血性脑卒中的发生率。Objective To evaluate correlation between premorbid hypertension control and the classification of ischemic stroke in patients with acute ischemic stroke and hypertension.Methods Data of 681 hospitalized hypertension patients with types of large-artery atherosclerosis(LAA)or small-vessel occlusion(SVO)stroke were analyzed retrospectively.Multivariate Logistic regression analysis was performed to analyze the relationship between premorbid hypertension control and LAA ischemic stroke.Results The uncontrolled hypertension patients had higher possibility in LAA ischemic stroke before attack of stroke(OR=1.607,95%CI,1.102 to 2.343).The possibilities of LAA ischemic stroke were higher in overweight(OR=1.498,95%CI,1.066 to 2.105),diabetic(OR=1.803,95%CI,1.215 to 2.674),and male(OR=1.804,95%CI,1.190 to 2.733)patients.Conclusion Standardized treatment and control of hypertension may reduce the incidence of type of LAA ischemic stroke.

关 键 词：高血压 缺血性脑卒中 大动脉粥样硬化型缺血性脑卒中 小血管闭塞型缺血性脑卒中 

分 类 号：R544.1[医药卫生—心血管疾病] R743.33[医药卫生—内科学]