右美托咪定预防剖宫产术患者椎管内麻醉期间寒战的临床研究  

Clinical Study of Dexmedetomidine for Preventing Chills During Intraspinal Anesthesia in Cesarean Section Patients

作　　者：孙孝斌 冯健[1] SUN Xiaobin;FENG Jian(Department of Anesthesiology,the First People's Hospital of Tianshui,Tianshhui,Gansu Province,741000 China)

机构地区：[1]天水市第一人民医院麻醉科,甘肃天水741000

出　　处：《中外医疗》2021年第17期57-59,共3页China & Foreign Medical Treatment

摘　　要：目的探讨右美托咪定对剖宫产术患者椎管内麻醉期间寒战的预防效果。方法随机选取2019年9月—2020年9月在该院行剖宫产术的80例孕产妇随机分为两组,对照组40例注入罗哌卡因+氯化钠+舒芬太尼的混合液,观察组40例注入罗哌卡因+右美托咪定+舒芬太尼的混合液,对比两组麻醉效果。结果观察组运动阻滞恢复时间(2.35±0.68)min短于对照组(3.18±0.44)min;寒战发生率低于对照组,差异有统计学意义(P<0.05)。观察组术后30 min(T1)和手术结束时(T2)平均动脉压(MAP)为(12.62±0.53)、(13.04±0.50)kPa高于对照组(11.58±0.36)、(11.83±0.52)kPa,心率(HR)低于对照组,两组间差异有统计学意义(P<0.05)。观察组镇静状态评分(4.72±1.23)分高于对照组(2.14±1.15)分,差异有统计学意义(t=9.690,P<0.001)。观察组麻醉不良反应发生率低于对照组,差异有统计学意义(P<0.05)。结论剖宫产术中应用右美托咪定可减少麻醉期间寒战发生,保持血流动力学稳定,提高镇静效果,减少不良反应。Objective To explore the preventive effect of dexmedetomidine on chills during intraspinal anesthesia in cesarean section patients.Methods From September 2019 to September 2020,80 pregnant women who underwent cesarean section in the hospital's were randomly selected and divided into two groups.In the control group,40 cases were injected with a mixture of ropivacaine+sodium chloride+sufentanil,40 cases in the observation group were injected with a mixture of ropivacaine+dexmedetomidine+sufentanil to compare the anesthesia effects of the two groups.Results The recovery time of the observation group was(2.35±0.68)min shorter than that of the control group(3.18±0.44)min.The incidence of chills was lower than that of control group,the difference was statistically significant(P<0.05).The mean arterial pressure(MAP)of the observation group were(12.62±0.53)points and(13.04±0.50)kPa higher than those of the control group(11.58±0.36)points and(11.83±0.52)kPa,and heart rate(HR)of the observation group were lower than those of the control group 30 min after operation(T1)and at the end of operation(T2).The difference between the two groups was statistically significant(P<0.05).The score of sedation in the observation group(4.72±1.23)points was higher than that in the control group(2.14±1.15)points,and the difference was statistically significant(t=9.690,P<0.001).The incidence of adverse anesthetic reactions in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The application of dexmedetomidine during cesarean section can reduce the occurrence of chills during anesthesia,maintain hemodynamic stability,improve sedation,and reduce adverse reactions.

关 键 词：右美托咪定 剖宫产术 椎管内麻醉 寒战 镇静 不良反应 

分 类 号：R614.4[医药卫生—麻醉学]