右美托咪定用于小儿麻醉对血流动力学及苏醒期躁动和术后疼痛的影响分析  

Analysis of the Effect of Dexmedetomidine Used in Pediatric Anesthesia on Hemodynamics,Restlessness during Recovery and Postoperative Pain

作　　者：林剑兵[1] 陈敏[1] 陈琴[1] 雷立华[1] 齐娟[1] LIN Jianbing;CHEN Min;CHEN Qin;LEI Lihua;QI Juan(The Second Department of Anesthesia,Fujian Provincial Hospital,Fuzhou,Fujian Province,350001 China)

机构地区：[1]福建省立医院麻醉二科,福建福州350001

出　　处：《中外医疗》2021年第17期75-77,共3页China & Foreign Medical Treatment

摘　　要：目的探讨右美托咪定用于小儿麻醉对血流动力学及苏醒期躁动和术后疼痛的影响分析。方法方便选取2019年1月—2020年6月在该院外科行全麻手术治疗的140例患儿随机分为两组,对照组单用七氟醚维持麻醉,观察组使用右美托咪定联合七氟醚维持麻醉,对比两组的麻醉及苏醒各指标、术中血流动力学指标变化、躁动及疼痛情况。结果两组麻醉时间、拔管时间、苏醒时间相比差异无统计学意义(P>0.05);观察组T1、T2、T3时的平均动脉压(MAP)及心率(HR)均明显低于对照组,差异有统计学意义(P<0.05);观察组术后躁动量化评分表(PAED)评分(6.84±3.05)分、面部表情量表法(FPS)评分(2.33±0.79)分及躁动发生率7.14%均明显低于对照组,两组比较差异有统计学意义(t=4.496、3.708,P<0.05;χ^(2)=9.985,P<0.05)。结论右美托咪定用于小儿麻醉效果良好,不影响麻醉及苏醒时间,能稳定术中血流动力学,降低术后疼痛程度及躁动发生率,增加小儿手术的舒适性及安全性。Objective To investigate the effect of dexmedetomidine used in pediatric anesthesia on hemodynamics,restlessness during recovery and postoperative pain.Methods 140 children who underwent general anesthesia in the hospital from January 2019 to June 2020 were randomly conveniently selected and divided into two groups.The control group was treated with sevoflurane alone to maintain anesthesia,and the observation group used dexmedetomide combined with sevoflurane to maintain anesthesia.The anesthesia and recovery indicators,intraoperative hemodynamic changes,restlessness and pain were compared between the two groups.Results There was no statistically significant difference in anesthesia time,extubation time,and recovery time between the two groups(P>0.05);the mean arterial pressure(MAP)and heart rate(HR)at T1,T2,and T3 of the observation group were significantly lower than those of the control group,the difference was statistically significant(P<0.05).The restlessness quantitative rating scale(PAED)score(6.84±3.05)points,faces rating scales(FPS)score(2.33±0.79)points and the incidence of agitation(7.14%)in the group were significantly lower than those in the control group.The difference between the two groups was statistically significant(t=4.496,3.708,P<0.05;χ^(2)=9.985,P<0.05).Conclusion Dexmedetomidine has a good effect in pediatric anesthesia,does not affect anesthesia and recovery time,can stabilize intraoperative hemodynamics,reduce postoperative pain and agitation,and increase the comfort and safety of pediatric surgery.

关 键 词：血流动力学 苏醒期躁动 术后疼痛 右美托咪定 小儿麻醉 

分 类 号：R726.1[医药卫生—儿科]