Hepatitis E virus in professionally exposed: A reason for concern?  

作　　者：Anna Mrzljak Ivan Balen Ljubo Barbic Maja Ilic Tatjana Vilibic-Cavlek 

机构地区：[1]Department of Gastroenterology and Hepatology,University Hospital Centre Zagreb,Zagreb 10000,Croatia [2]School of Medicine,University of Zagreb,Zagreb 10000,Croatia [3]Department of Gastroenterology and Endocrinology,General Hospital“Dr.Josip Bencevic”,Slavonski Brod 35000,Croatia [4]Faculty of Veterinary Medicine,University of Zagreb,Zagreb 10000,Croatia [5]Department of Epidemiology,Croatian Institute of Public Health,School of Medicine,University of Zagreb,Zagreb 10000,Croatia [6]Department of Virology,Croatian Institute of Public Health,School of Medicine,University of Zagreb,Zagreb 10000,Croatia

出　　处：《World Journal of Hepatology》2021年第7期723-730,共8页世界肝病学杂志（英文版）（电子版）

摘　　要：The zoonotic risk of hepatitis E virus(HEV)is well established.The HEV seroprevalence rates vary according to geographical region,assays used,and study cohorts.HEV infection is still underdiagnosed,implying the need to evaluate the disease's burden in the general population and specific risk groups,such as professionally exposed.Close contact with various animal reservoirs such as pigs,rabbits,sheep,dogs,wild boars,and deer has been associated with higher anti-HEV seroprevalence as a part of occupational exposure.While exact transmission routes remain to be determined,some general preventive measures such as proper hand hygiene,the usage of personal protective equipment,and the thermal processing of food before consumption should be followed.A“One-Health”multisectoral approach should be implemented to achieve optimal health and well-being outcomes,recognizing the interconnections between humans,animals,plants,and their shared environment,in which a vaccine against the zoonotic genotypes 3 and 4 and swine vaccination should be considered as a possible public health measure.This opinion review comprehensively addresses the HEV burden of professional exposure for butchers,slaughterhouse workers,veterinarians,farmers,hunters,and forestry workers delineates the current limits of protective work measures,and tackles future directions.

关 键 词：Hepatitis E virus Zoonotic infection Occupational disease VETERINARIANS Farmers Butchers Slaughterhouse workers Forestry workers HUNTERS 

分 类 号：R512.63[医药卫生—内科学]