巨乳缩小术患者肥胖程度与术后并发症关系的Meta分析  

Meta analysis on obesity level of macromastia patients and postoperative complication

作　　者：潘文兴 陆锦明 唐海安 陈钰欣 周强[1] PAN Wen-xing;LU Jin-mig;TANG Hai-an;CHEN Yu-xing;ZHOU Qiang(Department of Burns and Plastic Surgery,Zhaoqing First People's Hospital,Guangdong Province,526000,China)

机构地区：[1]肇庆市第一人民医院烧伤整形外科,广东肇庆526000

出　　处：《中国医疗美容》2021年第7期37-43,共7页China Medical Cosmetology

摘　　要：目的系统评价巨乳缩小术患者肥胖程度与术后并发症的关系。方法使用计算机检索Pubmed、Embase、Medline、Cochrance、WangFang、CNKI、万方医学、维普医学数据库,检索自建库至2020年11月已发表的关于巨乳缩小术患者不同肥胖程度术后并发症情况的中英文文献,由2位研究员独立进行文献筛选、提取相关数据,及风险偏倚评价后,采用RevMan5.3进行Meta分析。结果共纳入文献11篇,9193例患者,其中正常体质量534例、超重1199例、轻度肥胖2107例、中度肥胖1123例和重度肥胖779例。Meta分析结果显示,肥胖患者(BMI≥30.0 kg/m²)术后并发症风险高于非肥胖患者(BMI<30.0 kg/m²),(OR=1.51,95%CI:1.28~1.77,P<0.00001);超重患者(BMI 25.0~29.9 kg/m²)术后并发症风险高于正常体质量患者(BMI 18.5~24.9 kg/m²),(OR=1.43,995%CI:1.04~1.98,P=0.03);BMI(30.0~39.9 kg/m²)患者术后并发症风险高于非肥胖患者(BMI<30.0 kg/m²),(OR=1.37,95%CI:1.11~1.68,P=0.003);重度肥胖患者(BMI≥40.0 kg/m²)术后并发症风险高于非肥胖患者(BMI<30.0 kg/m²),(OR=2.80,95%CI:2.14~3.65,P<0.00001);肥胖患者(BMI≥30.0 kg/m²)术后感染风险高于非肥胖患者(BMI<30.0 kg/m²),(OR=1.51,95%CI:1.20~1.89,P=0.0004)。结论肥胖患者行缩乳术后手术并发症和组织感染的风险高于非肥胖患者,且随着肥胖程度的增加,风险逐渐增加。本研究结果可为术前患者教育、手术方式选择、术后护理程度的确定提供依据。Objective Analysis on the relationship between obesity level of macromastia patients and postoperative complication.Methods Searching Chinese and English literature related to the relationship between levels of macromastia patients and related postoperative complication in Pubmed,Embase,Medline,Cochrance,WangFang,CNKI,Wangfang Medicine,VTTMS Medicine before Nov 2020.RevMan 5.3 was used in Meta Analysis on the relationship after selection,extraction and risk deviation evaluation by two researchers independently.Results A total of 11 documents and 9193 patients were involved in the research,524,1199,2107,1123 and 779 of these patients were at the levels of normal weight,superheavy,Slightly obseity,Moderate obesity and Severe obesity respectively.After meta analysis,researchers found that the risk of postoperative complication for patients at the level of obesity(BMI≥30.0 kg/m²)is larger than that of people who are not fat(BMI<30.0 kg/m²),(OR=1.51,95%CI:1.28~1.77,P<0.00001);patients with BMI(30.0~39.9kg/m²)face with higher level of risk of complication than non-obesity patients(BMI<30.0 kg/m²),(OR=2.80,95%CI:2.14~3.65,P<0.00001);patients who are at the level of obesity(BMI≥30.0kg/m²)face with higher level of complication than people who are not at the level of obesity(BMI<30.0kg/m²),(OR=1.51,95%CI:1.20~1.89,P=0.0004).Conclusion Patients at the level of obesity face with higher level of complication and infection than people who are not fat after operation.In addition,the risk increase as the level of obesity rises.The results of the research can provide evidence for pre-operation education,choosing operation method and post-operation nurse.

关 键 词：META分析 巨乳缩小术 肥胖 体质量指数(BMI) 并发症 

分 类 号：R655.8[医药卫生—外科学]