系统性红斑狼疮伴广泛颅内钙化一例  

Systemic lupus erythematosus with extensive intracranial calcification:a case report

作　　者：赵宝景[1] 张振 覃文[1] 袁青青 邬秀娣 Zhao Baojing;Zhang Zhen;Qin Wen;Yuan Qingqing;Wu Xiudi(Department of Rheumatology,Ningbo First Hospital,Ningbo 315010,China)

机构地区：[1]宁波市第一医院风湿免疫科,315010

出　　处：《中华神经科杂志》2021年第8期825-828,共4页Chinese Journal of Neurology

摘　　要：系统性红斑狼疮患者合并广泛颅内钙化较罕见。文中报道1例系统性红斑狼疮继发抗磷脂抗体综合征患者,合并对称性广泛颅内钙化,并进行文献复习,探讨系统性红斑狼疮合并广泛颅内钙化的发病机制。通过文献复习并结合本病例研究发现,神经精神狼疮病情活动及抗磷脂抗体阳性可能是颅内钙化的危险因素,维持病情缓解及规范抗凝治疗非常重要。Extensive intracranial calcification is rare in patients with systemic lupus erythematosus.This article reported a patient with antiphospholipid antibody syndrome secondary to systemic lupus erythematosus,complicated with bilateral symmetrical extensive intracranial calcification.By reviewing literature,the results suggested that the flare of neuropsychiatric systemic lupus erythematosus and the presence of antiphospholipid antibodies may be risk factors for intracranial calcification.Therefore,in order to prevent the formation of intracranial calcification,it is necessary to maintain continuous disease remission and anticoagulant therapy.

关 键 词：红斑狼疮 系统性 神经精神 钙化 抗体 抗磷脂 

分 类 号：R593.241[医药卫生—内科学]