Nedaplatin-induced syndrome of inappropriate secretion of antidiuretic hormone:A case report and review of the literature  

作　　者：Lei Tian Li-Ya He Hong-Zhen Zhang 

机构地区：[1]Department of Oncology,Hebei General Hospital,Shijiazhuang 050051,Hebei Province,China

出　　处：《World Journal of Clinical Cases》2021年第23期6810-6815,共6页世界临床病例杂志

摘　　要：BACKGROUND Syndrome of inappropriate secretion of antidiuretic hormone(SIADH)is relatively common in several cancers,such as small cell lung cancer.However,nedaplatin-induced SIADH is rare.We describe a case of SIADH mediated by nedaplatin.CASE SUMMARY A 54-year-old female with nasopharyngeal carcinoma was treated with nedaplatin and developed severe hyponatremia due to SIADH.The side effects were successfully treated by fluid restriction and sodium supplementation.CONCLUSION This case report highlights the importance of cautiously treating life-threatening hyponatremia in patients treated with nedaplatin.

关 键 词：NEDAPLATIN Syndrome of inappropriate secretion of antidiuretic hormone HYPONATREMIA Fluid restriction Sodium supplementation Case report 

分 类 号：R969[医药卫生—药理学]