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作 者:苏洋 丁佑铭[1] Su Yang;Ding Youming(Department of Hepatobiliary Surgery,Renmin Hospital of Wuhan University,Hubei Wuhan 430060,China)
机构地区:[1]武汉大学人民医院肝胆外科,湖北武汉430060
出 处:《腹部外科》2021年第4期318-321,F0003,共5页Journal of Abdominal Surgery
基 金:国家十二五科技支撑计划项目(2012BAD31B08)。
摘 要:原发性肝癌是一种常见的消化系统恶性肿瘤,其发病率高,进展迅速,预后差。由于肝癌细胞代谢消耗导致机体的营养缺失、肌肉蛋白质大量分解,病人可能会出现肌少症。近年来有研究表明,原发性肝癌病人治疗的预后与肌少症密切相关。该文将结合国内外最新研究报道,对肌少症的定义、诊断及肌少症与肝癌治疗预后的关系进行综述。Primary livercancer is a common malignant tumor of digestive system with high incidence,rapid progression and poor prognosis.Due to the loss of nutrients in the body and the breakdown of muscle protein due to the metabolic consumption of liver cancer cells,the patient may develop sarcopenia.Recent studies have shown that the prognosis of primary liver cancer patients is closely related to sarcopenia.Here the definition and diagnosis of sarcopenia were discussed along with the relationship between sarcopenia and the treatment and prognosis of liver cancer.
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