基于肝主疏泄理论探析硒与弥漫性毒性甲状腺肿的相关性  

The Correlation between Selenium and Diffuse Toxic Goiter based on the Theory of Liver Regulation and Drainage

作　　者：余卉 赖倚文 刘庆阳[2] 高天舒[2] YU Hui;LAI Yiwen;LIU Qingyang;GAO Tianshu(Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China;Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110032,Liaoning,China)

机构地区：[1]辽宁中医药大学,辽宁沈阳110847 [2]辽宁中医药大学附属医院,辽宁沈阳110032

出　　处：《实用中医内科杂志》2021年第7期46-48,共3页Journal of Practical Traditional Chinese Internal Medicine

基　　金：辽宁省博士启动基金(20161191)。

摘　　要：弥漫性毒性甲状腺肿(Graves病,GD)属"瘿病"范畴,是由情志内伤或水土或遗传因素所致肝失疏泄,气机郁滞,津液凝聚成痰,壅滞颈前的一种疾病,其主要责之于肝的疏泄功能失常而导致肝气郁滞。GD患者存在体内低硒水平现象,硒水平低亦可引起肝的疏泄功能异常而致GD患病率升高或治疗及转归不佳,可通过补充硒来改善肝郁症状从而提高治疗GD的效果。Diffuse toxic goiter(GD) belongs to the category of "gall disease", which is caused by internal emotional injury or water and soil, genetic factors such as liver loss and drainage, stagnation of qi mechanism, aggregation of body fluid into sputum, and obstruction of the neck. It is mainly responsible for liver drainage dysfunction resulting in liver qi stagnation. There is a phenomenon of low selenium level in GD patients. Low selenium level can cause liver loss and drainage, leading to an increase in the prevalence of GD or poor treatment and outcome. Selenium supplementation can improve the symptoms of liver depression so as to improve the effect of GD treatment.

关 键 词：GRAVES病 肝主疏泄 硒 

分 类 号：R265[医药卫生—中医外科学]