基于WHO-FICs心肺运动试验在肺癌患者中应用的Scoping综述  

Application of Cardiopulmonary Exercise Testing in Patients with Lung Cancer Based on World Health Organization Family International Classifications:A Scoping Review

作　　者：王丹 李瑾[2] 高民 张明[1,2] 陈猛 张一帆[3] 夏露露[1] 陈伟[2] WANG Dan;LI Jin;GAO Min;ZHANG Ming;CHEN Meng;ZHANG Yi-fan;XIA Lu-lu;CHEN Wei(Xuzhou Rehabilitation Hospital Affiliated to Xuzhou Medical University,Xuzhou,Jiangsu 221010,China;Deartment of Rehabilitation Medicine,the Clinical School of Xuzhou Medical University,Xuzhou,Jiangsu 221009,China;Department of Radiotherapy,Xuzhou Central Hospital,the Clinical School of Xuzhou Medical University,Xuzhou,Jiangsu 221009,China)

机构地区：[1]徐州医科大学附属徐州康复医院,江苏徐州市221010 [2]徐州市中心医院,徐州医科大学徐州临床学院康复医学科,江苏徐州市221009 [3]徐州市中心医院,徐州医科大学徐州临床学院放疗科,江苏徐州市221009

出　　处：《中国康复理论与实践》2021年第8期923-935,共13页Chinese Journal of Rehabilitation Theory and Practice

基　　金：徐州市引进临床医学专家团队项目(No.2018TD007);徐州市科技计划项目(No.KC18184,No.KC20136)。

摘　　要：目的基于世界卫生组织国际健康分类家族(WHO-FICs)理论,分析心肺运动试验(CPET)在肺癌患者中的应用。方法检索2013年1月至2021年4月,PubMed、WebofScience、中国知网和万方数据库关于CPET在肺癌患者中应用的研究。采用Scoping综述方法分析CPET应用于肺癌患者时的适应证与禁忌证、运动功能障碍、肺康复干预措施、评价方法和指标以及环境因素等。结果基于WHO-FICs框架,本文主要从5个方面对纳入文献进行分析。主要疾病为不同病理类型的非小细胞肺癌(NSCLC)(2C25),肺癌最常见的并发症是慢性阻塞性肺疾病(COPD)(CA22);肺癌患者进行CPET的障碍主要包括身体结构和功能、活动和参与障碍;基于CPET的肺康复运动训练方法被划分为治疗类、预防类和健康促进类;评价工具及指标采用摄氧量、二氧化碳排出量、氧脉搏、心率、血压、心电图、Borg量表、6分钟步行测试、健康调查简表(SF-36)等,并提供环境因素的分类和描述。结论CPET在肺癌中的应用主要包括术前评估及预后预测、运动处方制定及运动效果评估、抗癌治疗影响评估三个方面。基于WHO-FICs理论体系,CPET应用对象主要为NSCLC,肺癌最常见的并发症是COPD;肺癌肺康复是以功能障碍和需求为导向,基于CPET评估结果进行个体化治疗类、预防类和健康促进类的肺康复运动训练,旨在提高患者整体功能,优化肺癌患者健康结局。Objective To analyze the clinical application and main roles of Cardiopulmonary Exercise Test(CPET)in patients with lung cancer based on the theory of the World Health Organization Family International Classifications(WHO FICs).Methods An evidence-based scoping review was implemented.Literatures related to the applications of CPET in patients with lung cancer were retrieved,from databases including PubMed,Web of Science,CNKI and Wanfang data;from January,2013 to April,2021.The indications,contraindications,motor dysfunction,pulmonary rehabilitation interventions,evaluation methods and indicators,and the environment factors of CPET applicated in patients with lung cancer was reviewed based on WHO-FICs framework.Results This paper analyzed the included literatures from five aspects:the type of disease,functioning,pulmonary rehabilitation exercise interventions,functioning evaluation and environment factors.The major diseases included different pathological types of non-small cell lung cancer(NSCLC)(2C25),and the most common complication of lung cancer was chronic obstructive pulmonary disease(COPD)(CA22).The obstacles of CPET conducted in lung cancer patients mainly included physical structure and functional activities and participation obstacles.Pulmonary rehabilitation based on the CPET was divided into therapeutic,preventive and health promotion interventions.The evaluation tools and indicators were oxygen intake,carbon dioxide output,oxygen pulse,heart rate,blood pressure,electrocardiogram,Borg Scale,6-minute Walking Test,the MOS Item Short Form Health Survey(SF-36),etc.The classification and description of environmental factors were provided.Conclusion The application of CPET in lung cancer mainly included preoperative evaluation and prognosis prediction,exercise prescription formulation and exercise effect assessment,anti-cancer treatment impact assessment.Based on WHO-FICs theory system,the applications of CPET mainly involved NSCLC,and COPD was the most common complication of lung cancer.Pulmonary rehabilit

关 键 词：心肺运动试验 肺癌 世界卫生组织国际健康分类家族 肺康复 心肺适能 范围综述 

分 类 号：R563[医药卫生—呼吸系统]