绝经后子宫内膜增厚与子宫内膜病变的临床分析  

Clinical analysis of endometrial thickness and endometrial lesions in postmenopausal women

作　　者：宁林莹[1] NING Lin-ying(Xinyi People’s Hospital,Xinyi 525300,China)

机构地区：[1]信宜市人民医院,525300

出　　处：《中国实用医药》2021年第24期53-56,共4页China Practical Medicine

摘　　要：目的探讨绝经后子宫内膜增厚与子宫内膜病变情况。方法102例子宫内膜厚度≥4 mm的绝经妇女,为其进行诊断性刮宫,分析病理检查结果。结果年龄>60岁与≤60岁、绝经时间>3年与≤3年、体重>60 kg与≤60 kg、体质量指数>25 kg/m^(2)与≤25 kg/m^(2)、是否有激素替代治疗、是否有高血压、是否有糖尿病绝经妇女的子宫内膜厚度比较,差异均无统计学意义(P>0.05)。使用他莫昔芬绝经妇女子宫内膜厚度(13.17±8.59)mm高于未使用他莫昔芬绝经妇女的(9.14±4.07)mm,差异有统计学意义(P<0.05)。102例妇女中,子宫内膜厚度≥4 mm且<5 mm的妇女无子宫内膜癌患者;子宫内膜厚度5~7 mm的妇女有子宫内膜癌4例;子宫内膜厚度8~9 mm的妇女有子宫内膜癌7例;子宫内膜厚度≥10 mm的妇女有11例子宫内膜癌。内膜癌发生几率会伴随子宫内膜厚度的增加而逐渐提升。结论使用他莫昔芬会增加绝经后子宫内膜厚度,且内膜癌发生几率会伴随子宫内膜厚度的增加而逐渐提升。子宫内膜厚度≥4 mm且<10 mm者,出现内膜癌的几率相对偏低,针对该类妇女的病理检查可倾向于保守,并注意排查其高危因素;子宫内膜厚度≥10 mm者,内膜癌发生几率相对较高,应积极采取诊断性刮宫。Objective To discuss the endometrial thickness and endometrial lesions in postmenopausal women.Methods 102 cases of menopausal women with endometrial thickness≥4 mm all underwent diagnostic curettage,and the pathological examination results were analyzed.Results There were no statistically significant differences in endometrial thickness of the postmenopausal women between age>60 years old and≤60 years old,menopausal time>3 years and≤3 years,body weight>60 kg and≤60 kg,body mass index>25 kg/m^(2)and≤25 kg/m^(2),whether there was hormone replacement therapy,high blood pressure and diabetes or not(P>0.05).The endometrial thickness of postmenopausal women using tamoxifen was(13.17±8.59)mm,which was significantly higher than(9.14±4.07)mm of menopausal women not using tamoxifen,and the difference was statistically significant(P<0.05).Among 102 women,women with endometrial thickness≥4 mm and<5 mm had no endometrial cancer,and there were 4 cases of endometrial cancer in women with endometrial thickness of 5-7 mm,7 cases of endometrial cancer in women with endometrial thickness of 8-9 mm,11 cases of endometrial cancer in women with endometrial thickness≥10 mm.The incidence of endometrial cancer will gradually increase with the increase of endometrial thickness.Conclusion Tamoxifen can increase the endometrial thickness in postmenopausal women,and the incidence of endometrial cancer will gradually increase with the increase of endometrial thickness.The risk of endometrial cancer is relatively low in women with endometrial thickness≥4 mm and<10 mm.The pathological examination of these women can be conservative,and the high-risk factors should be investigated.The incidence of endometrial cancer is relatively high in women with endometrial thickness≥10 mm,and diagnostic curettage should be actively taken.

关 键 词：子宫内膜增厚 子宫内膜病变 绝经 

分 类 号：R711.74[医药卫生—妇产科学]