功能CT成像术前评估肺癌生物学行为的研究进展  

Research Progress of Functional CT Imaging in Preoperative Assessment of Pathological Behavior of Lung Cancer

作　　者：孙丹丹 杨杨 燕晶晶 于晶[1] 伍建林[1] SUN Dandan;YANG Yang;YAN Jingjing;YU Jing;WU Jianlin(Department of Radiology,Zhongshan Hospital Affiliated to Dalian University,Dalian 116001,China;Department of Radiology,The First Affiliated Hospital of Chongqing Medical College,Chongqing 400060,China)

机构地区：[1]大连大学附属中山医院放射科,辽宁大连116001 [2]重庆医药高等专科学校附属第一医院放射科,重庆400060

出　　处：《CT理论与应用研究（中英文）》2021年第3期395-402,共8页Computerized Tomography Theory and Applications

基　　金：2019年SKY影像科研基金(Z-2014-07-1912-13)。

摘　　要：肺癌是临床常见的恶性肿瘤,有较高的发病率及死亡率。评估肺癌的生物学行为对选择治疗方案、判断疗效及预后具有重要意义,但病理组织标本的获取依赖有创操作且存在诸多问题。目前,应用较先进的功能CT成像技术在术前无创性地评估肺癌的生物学行为已成为当下研究的热点,本文就功能CT成像的一般原理及在评估肺癌生物学行为方面的应用予以综述。Lung cancer is a common clinical malignant tumor, and it has a high morbidity and mortality rate. Evaluating the pathological behavior of lung cancer is of great significance for selecting treatment options, judging the efficacy and prognosis, but the acquisition of pathological tissue specimens depends on invasive operations and there are many problems. At present, the application of more advanced functional CT imaging technology to non-invasively assess the pathological behavior of lung cancer before surgery has become a hot research topic. This article reviews the general principles of functional CT imaging and its application in evaluating the pathological behavior of lung cancer.

关 键 词：功能成像 病理学因子 微血管密度 血管内皮生长因子 

分 类 号：R814[医药卫生—影像医学与核医学]