福美双对肉鸡股骨生长发育的影响及巴戟天多糖保护效果的研究  

Effect of Thiram on Femoral Growth and Development in Broiler Chickens and Protective Efficacy of Morinda officinalis Polysaccharide

作　　者：曹芹芹 岳珂 林露茜 徐婷婷 张朝栋 郑晶晶 孔安安 仝宗喜[1] 黄淑成 CAO Qin-qin;YUE Ke;LIN Lu-xi;XU Ting-ting;ZHANG Chao-dong;ZHENG Jing-jing;KONG An-an;TONG Zong-xi;HUANG Shu-cheng(College of Veterinary Medicine,Henan Agricultural University,Zhengzhou 450002,China)

机构地区：[1]河南农业大学动物医学院,河南郑州450002

出　　处：《畜牧与饲料科学》2021年第4期110-117,共8页Animal Husbandry and Feed Science

基　　金：河南农业大学青年英才基金资助项目(30500421);河南省高等学校重点科研项目基础研究专项计划(21A230013)。

摘　　要：[目的]探究福美双对肉鸡股骨生长发育的影响,评价巴戟天多糖(Morinda officinalis polysaccharide,MOP)对福美双诱导的肉鸡股骨损伤的保护效果。[方法]将300只1日龄AA肉鸡随机分为对照组、福美双组以及低、中、高剂量MOP组,每组3个重复,每个重复20只鸡。对照组全程饲喂基础饲粮;试验第4~7天,福美双组和各MOP组在基础饲粮中添加50 mg/kg福美双;在整个试验期内,低、中、高剂量MOP组分别在饮水中添加250、500、1000 mg/L MOP。试验期为15 d。观察各组肉鸡临床表现;在试验第7、11、15天进行股骨和血液样品采集,对股骨进行形态学观察,测定股骨剪切力、物理指标(重量、长度、体积、密度)、干物质含量、钙磷含量、灰分(DM)、灰分(FM)、灰分密度,检测血浆钙离子和无机磷含量。利用统计学方法对各组试验数据进行比较分析。[结果]福美双组肉鸡出现跛行,严重者无法站立,股骨明显比对照组肉鸡短。试验第7天,与对照组相比福美双组股骨剪切力显著(P<0.05)降低。在整个试验期间,福美双组股骨的4项物理指标均显著(P<0.05)低于对照组;试验第11天低剂量MOP组的股骨重量显著(P<0.05)高于福美双组,试验第15天低剂量MOP组和中剂量MOP组的股骨长度显著(P<0.05)高于福美双组。试验第7天,福美双组股骨钙含量显著(P<0.05)低于对照组;试验第11天,福美双组股骨干物质含量、灰分(FM)、灰分密度显著(P<0.05)低于对照组;试验第11天,高剂量MOP组与福美双组相比股骨干物质含量显著(P<0.05)增加。试验第15天中剂量MOP组的血浆无机磷含量与对照组相比显著(P<0.05)升高。[结论]福美双通过降低股骨强度、物理指标以及钙沉积,抑制肉鸡股骨生长发育;MOP对福美双诱导的肉鸡股骨损伤具有一定的保护和缓解效果。[Objective]To assess the effect of thiram on femoral growth and development in broiler chickens,and to evaluate the protective efficacy of Morinda officinalis polysaccharide(MOP)against the femoral injuries induced by thiram.[Method]A total of 300 one-day-old AA broiler chickens were randomly divided into control group,thiram model group,and low-,moderate-,high-dosage MOP treatment groups.There were 3 replicates for each group and 20 broiler chickens for each replicate.The control group was fed with a basal diet;from 4th to 7th days of the experiment,thiram model group and three MOP treatment groups were fed with basal diets added with 50 mg/kg thiram;during the whole experiment,250,500 and 1000 mg/L MOP were supplied for low-,moderate-and high-dosage MOP treatment groups in drinking water.The experiment lasted for 15 days.The clinical manifestations of the broiler chickens in each group were observed;on 7th,11th and 15th days of the experiment,the femur and blood samples were collected;the morphological observation of femur was carried out,the shearing force,physical indexes(weight,length,volume and density),dry matter contents,calcium and phosphorus contents,ash contents(DM),ash contents(FM),and ash densities of the femur samples were determined,and the plasma contents of calcium and inorganic phosphorus were tested.The inter-group differences of the experimental data were statistically analyzed.[Result]The broiler chickens in thiram model group appeared claudication,the serious ones were unable to stand,and had shorter femur compared with those in control group.On 7th day of the experiment,the femur shearing force of thiram model group was significantly(P<0.05)decreased compared with control group.During the whole experiment,the 4 physical indexes of thiram model group were significantly(P<0.05)lower than those of control group;the femur weights of low-dosage MOP treatment group were significantly(P<0.05)higher than those of thiram model group on 11th day of the experiment,and the femur lengths of low-and mode

关 键 词：福美双 巴戟天多糖 肉鸡 股骨 钙磷含量 灰分含量 

分 类 号：S858.317.16[农业科学—临床兽医学]