A case report of autochthonous Q fever with pneumonia and hepatitis in northeastern China  

作　　者：Yuan Gao Lihe Che Zedong Wang Junqi Niu Wei Wei Mingxin Song Quan Liu 

机构地区：[1]Department of Emerging Infectious Diseases,The First Hospital of Jilin University,Changchun 130062,China [2]Department of Hepatology,The First Hospital of Jilin University,Changchun 130062,China [3]Institute of Virology and AIDS Research,First Hospital of Jilin University,Changchun 130062,China [4]College of Veterinary Medicine,Northeast Agricultural University,Harbin 150030,China [5]School of Life Sciences and Engineering,Foshan University,Foshan 528225,China

出　　处：《Biosafety and Health》2021年第3期179-182,共4页生物安全与健康（英文）

基　　金：supported by the National Key R&D Program of China(2017YFD0501700);the Pearl River Talent Recruitment Program in Guangdong Province of China(2019CX01N111).

摘　　要：There are only a few case reports of Q fever caused by Coxiella burnetii in China,despite the nature as a ubiquitous zoonotic disease worldwide.In the northeast part of China,a 52-year-old male presented with fever,cough,shortness of breath,and sputum production,accompanied by headache,dizziness,chill,myalgia,and arthralgia.Chest computed tomography images showed pneumonia accompanied by bilateral scattered infiltrates and localized upper-lobe emphysema.The abnormal liver function was indicated by the increased levels of alanine aminotransferase and aspartate aminotransferase.Through high-throughput sequencing and molecular detection,Coxiella burnetii was positive in the patient's blood specimens.After treatment with moxifloxacin hydrochloride and vidarabine monophosphate for 12 days,the patient completely recovered.To our knowledge,this was the first reported case of Q fever with pneumonia and hepatitis in this country.

关 键 词：Q fever Coxiella burnetii PNEUMONIA HEPATITIS China 

分 类 号：R512.8[医药卫生—内科学] R563.1[医药卫生—临床医学] R575.3