介入再通术治疗输卵管阻塞性不孕症的效果及影响术后妊娠率的相关因素分析  

Curative Efficacy of Interventional Recanalization in Treatment of Patients with Oviduct Obstructive Infertility and Influencing Factors of Postoperative Pregnancy Rate

作　　者：李娟 王佳茹 谢婷婷 LI Juan;WANG Jia-ru;XIE Ting-ting(Department of Gynecology,the First Affiliated Hospital of PLA Air Force Military Medical University,Xi'an 710032,China)

机构地区：[1]空军军医大学第一附属医院妇科,西安710032

出　　处：《解放军医药杂志》2021年第8期92-95,100,共5页Medical & Pharmaceutical Journal of Chinese People’s Liberation Army

基　　金：陕西省重点研发计划项目(2017SF-019)。

摘　　要：目的探讨介入再通术治疗输卵管阻塞性不孕症的效果及影响术后妊娠率的相关因素。方法选取2017年6月—2019年6月我院收治的输卵管阻塞性不孕症67例,根据治疗方式分为观察组34例和对照组33例,对照组采取输卵管通液治疗,观察组采取输卵管介入再通术。比较2组治疗后输卵管复通率、受孕成功率及并发症发生率。按照治疗后妊娠情况分为妊娠组36例和非妊娠组31例,影响妊娠组和非妊娠组不同年龄患者术后妊娠率的危险因素采用Logistic回归分析。结果观察组输卵管复通率、受孕成功率高于对照组(P<0.05)。观察组并发症发生率低于对照组(P<0.05)。不孕类型、盆腔弥散情况是影响年龄<35岁的输卵管阻塞性不孕症患者介入再通术后成功妊娠的独立危险因素(P<0.01,P<0.05)。结论对输卵管阻塞性不孕症采取介入再通术治疗,可有效疏通输卵管阻塞,提高受孕成功率,术后并发症发生率低。年龄<35岁不孕症中,不孕类型及盆腔弥散是影响输卵管介入再通术后成功受孕的独立危险因素,应给予充分关注。Objective To explore curative efficacy of interventional recanalization in treatment of patients with oviduct obstructive infertility(OOI)and influencing factors of postoperative pregnancy rate.Methods A total of 67 patients with OOI admitted between June 2017 and June 2019 were enrolled in this study,and the patients were divided into observation group(n=34)and control group(n=33)according to different therapeutic methods.Control group was treated with hydrotubation,while observation group was treated with oviduct interventional recanalization.Oviduct recanalization rate,fertilization success rate and incidence rate of complications after treatment were compared between two groups.According to pregnancy results after treatment,they were divided into pregnancy group(n=36)and non-pregnancy group(n=31).Risk factors affecting postoperative pregnancy rate of patients with different ages in pregnancy and non-pregnancy groups were analyzed by logistic regression analysis.Results Oviduct recanalization rate and fertilization success rate in observation group were significantly higher than those in control group(P<0.05).Incidence rate of complications in observation group was significantly lower than that in control group(P<0.05).Types of infertility and conditions of pelvic dispersion were independent risk factors affecting successful pregnancy of women with OOI younger than 35 years old after interventional recanalization(P<0.01,P<0.05).Conclusion Interventional recanalization in treatment of patients with OOI may effectively dredge oviduct obstruction and increase fertilization success rate with a low incidence rate of postoperative complications.Among patients younger than 35 years old,types of infertility and conditions of pelvic dispersion are independent risk factors affecting successful pregnancy after interventional recanalization,which should be paid more attention.

关 键 词：不孕症 女性 输卵管阻塞 输卵管介入再通术 妊娠率 危险因素 并发症 

分 类 号：R711.6[医药卫生—妇产科学]