有机中间体2-噻吩甲醛的合成研究  

Synthesis of Organic Intermediate 2- thiophene Formaldehyde

作　　者：陈弘祥 何培迎 叶忠文[1] 骆建 CHEN Hongxiang;HE Peiying;YE Zhongwen;LUO Jian(Jiangsu Lanfeng Biochemical Co.,Ltd.,Jiangsu Xinyi221400,China)

机构地区：[1]江苏蓝丰生物化工股份有限公司,江苏新沂221400

出　　处：《现代农药》2021年第4期24-25,29,共3页MODERN AGROCHEMICALS

摘　　要：探讨了以噻吩、DMF、光气为原料,在引入少量催化剂的作用下,合成噻吩甲醛的新方法,并考察了不同条件下对反应影响。同时,笔者对后处理进行了探讨,在优化反应条件下,产品含量大于99%,收率大于90%。该工艺操作平稳,后处理简单,避免了使用大量溶剂,成本低,适合工业化生产。This paper discusses the thiophene,DMF,phosgene as raw materials.The introduction of a small amount of catalyst,the new method of synthesis of thiophene formaldehyde,reaction under different conditions,as well as the post-processing are discussed in this paper.Under the optimized reaction conditions,product content is greater than 99%and the yield is greater than 90%,with the smooth operation,simple post-processing,which avoid using a large amount of solvent.The method is low cost and suitable for industrial production.

关 键 词：相转移 噻吩 光气 噻吩甲醛 蒸馏 

分 类 号：TQ251.2[化学工程—有机化工]