新型冠状病毒肺炎确诊与疑似病例临床特征和影像学比较  

Comparison of clinical features and imaging of confirmed and suspected cases of COVID-19

作　　者：苏清 李鹏程 付军 王智超[1] SU Qing;LI Peng-cheng;FU Jun;WANG Zhi-chao(J.Department of Emergency Medicine,Wuhan First Hospital,Wuhan,Hubei 430022;Department of Blood Transfusion Medicine,Wuhan First Hospital,Wuhan,Hubei 430022;Department of Radiology,Wuhan First Hospital,Wuhan,Hubei 430022,China)

机构地区：[1]武汉市第一医院急诊科,湖北武汉430022 [2]武汉市第一医院输血科,湖北武汉430022 [3]武汉市第一医院放射科,湖北武汉430022

出　　处：《热带医学杂志》2021年第7期896-899,共4页Journal of Tropical Medicine

基　　金：武汉市卫生健康委员会项目(WX17D02)。

摘　　要：目的探讨新型冠状病毒肺炎(COVID-19)的流行病学、临床特征、血液化验及胸部CT等特点,为降低漏诊率,提高诊断率提供科学参考依据。方法回顾性分析了武汉市第一医院2020年2月12日-3月1日入院的122例COVID-19患者,按COVID-19第7版诊疗方案分为确诊组(n=80)和疑似组(n=42)。结果患者年龄1692岁,两组年龄差异无统计学意义(P>0.05)。女性66例(54.1%)。患者均有武汉疫区生活居住史,34例(27.9%)有确诊患者密切接触史,其中25例(73.5%)为家庭聚集性发病。常见的临床表现有发热(72.1%)、咳嗽(66.4%)、呼吸困难(37.7%),64例(52.5%)患者有基础疾病。确诊组肌酸激酶同工酶、肌酸激酶均高于疑似组(P<0.05)。118例(96.7%)胸部CT有异常表现,疑似组有磨玻璃阴影表现高于确诊组(P<0.05)。结论确诊组更易并发心肌损伤。COVID-19胸部CT检查阳性率较高,有助COVID-19的筛查。肺磨玻璃阴影是COVID-19较典型的影像学表现。Objective To explore the characteristics of epidemiology,clinical manifestations,blood tests and chest CT manifestations of patients with corona virus disease 2019(COVID-19),and provide a scientific reference basis to reduce the missed diagnosis rate and improve the diagnosis rate.Methods 122 patients who were admitted to the Wuhan No.1 hospital from February 12,2020 to March 1,2020 were retrospectively studied;they were divided into the confirmed group(n=80)and the suspected group(n=42)according to the 7 th edition of the Guideline of COVID-19 Diagnosis and Treatment.Results The age distribution was 16 to 92 years old.66(54.1%)patients were female.All the patients had a history of living in the epidemic area in Wuhan;34(27.9%)cases had a history of close contact with the confiremed patient;among which,25(73.5%)cases were familial cluster.Common symptoms of illness were fever(72.1%),cough(66.4%),and dyspnoea(37.7%).64(52.5%)patients had at least one underlying diseases.We compare 12 blood test indicators in two groups;the creatine kinase isoenzyme,creatine kinase of the confirmed group was higher than that of the suspected group(P<0.05),118(96.7%)cases had abnormal in chest CT;the suspected group had ground glass shadow was higher than that of the confirmed group(P<0.05).Conclusions The confirmed group was more likely to be complicated with myocardial injury.The positive rate of chest CT was high,which could help the screening of COVID-19.The ground glass shadow of the lung was a typical imaging manifestation of COVID-19.

关 键 词：SARS-CoV-2 COVID-19 核酸检测 胸部CT 

分 类 号：R563[医药卫生—呼吸系统]