基于弹性支撑式体外凝血检测传感器疲劳极限寿命评估方法  

An elastic support-based method of fatigue life limit assessment for in-vitro coagulation sensors

作　　者：王哲[1] 陈启梦[1] 孟祥凯 赵梓朝 于源华[1] Wang Zhe;Chen Qimeng;Meng Xiangkai;Zhao Zizhao;Yu Yuanhua(Changchun University of Science and Technology,Changchun 130022,China;Jilin Institute of Metrology,Changchun 130103,China)

机构地区：[1]长春理工大学,长春130022 [2]吉林省计量科学研究院,长春130103

出　　处：《仪器仪表学报》2021年第5期121-130,共10页Chinese Journal of Scientific Instrument

基　　金：吉林省科技发展计划项目(20200404180YY);吉林省科技发展计划项目(20200602050ZP)资助。

摘　　要：针对体外凝血检测传感器结构核心元件弹性支撑易遭受变形而引起传感器失效的关键问题,建立一种基于传感器疲劳寿命和断裂方式的可靠性寿命评估方法。本文根据体外凝血检测传感器工作原理及结构特点,对传感器可靠性进行失效分析,通过建立可靠性理论分析力学模型,推导由弹性支撑应变传递系数引起的凝血检测传感器极限传感寿命判断准则表达式,采用有限元分析法对弹性支撑进行谐响应分析,以传感器疲劳寿命第15等级作为失效阈值,提出基于传感器弹性支撑的极限传感寿命测试方法。利用本方法对双通道体外凝血检测传感器进行了1.08亿次应力疲劳实验,弹性支撑的螺旋弹片满量程相对有效误差分别为3.89%、3.79%、4.75%,按照4.5%为满量程相对误差分界线,结果表明该弹片已经到了应力寿命极限,其余两片均未达到安全阈值水平,所以传感器的疲劳寿命可靠性约为1.08亿次,与仿真数据基本吻合,验证了建立的体外凝血检测传感器极限传感寿命评估方法可以满足传感器失效分析的要求,为提升此类传感器的研制工艺提供核心技术。As a core component of in-vitro coagulation sensor structure,the sensor failure is easily caused by the deformation of its elastic support.To address this issue,this paper proposes a reliability life assessment method,which is based on the fatigue life and breakage mode of the sensor.Failure analysis is performed on the sensor reliability according to the operating principle and structural features of the in-vitro coagulation sensor.By formulating the mechanical model for theoretical reliability analysis,the expression of determination criterion for the life limit of coagulation sensor is derived,which is attributable to the strain transfer coefficient of elastic support.The harmonic response of the elastic support is analyzed by the finite element analysis.An elastic support-based method for assessing the ultimate sensing life is proposed by taking the 15 th level of sensor fatigue life as the failure threshold.By using this method,108 million stress fatigue tests are implemented on the dual-channel in-vitro coagulation sensor.The full-scale relative effective errors of spiral clips for the elastic support are 3.89%,3.79%and 4.75%,respectively.Under the 4.5%boundary of the full-scale relative effective error,the results indicate that a clip has reached its stress life limit,while other two clips are yet to reach the safety threshold level.Thus,the fatigue life reliability of the sensor is approximately 108 million times,which basically agrees with the simulation data.These results verify that the proposed life limit assessment method for the in-vitro coagulation sensor conforms to the requirements of sensor failure analysis,which also offers a core technique for improving the development procedure of such sensors.

关 键 词：传感器 弹性支撑 可靠性 寿命极限 

分 类 号：TH165.4[机械工程—机械制造及自动化]