气象和空气污染物对原发性气胸发病的影响  

Effect of meteorology and air pollutants on incidence of primary spontaneous pneumothorax

作　　者：王亚芹 白风霞 梁璐[2] 付桂琴 杨伟红[2] 张孟繁 刘思亮 黄家惠 Wang Yaqin;Bai Fengxia;Liang Lu;Fu Guiqin;Yang Weihong;Zhang Mengfan;Liu Siliang;Huang Jiahui(Clinical Medical School,Affiliated Hospital of Hebei University,Baoding 071000,China;Department of Emergency,Affiliated Hospital of Hebei University,Baoding 071000,China;Hebei Provincial Meteorological Service Center,Shijiazhuang 050021,China)

机构地区：[1]河北大学附属医院/临床医学院,保定071000 [2]河北大学附属医院急诊科,保定071000 [3]河北省气象服务中心,石家庄050021

出　　处：《国际呼吸杂志》2021年第15期1132-1137,共6页International Journal of Respiration

基　　金：国家科技基础资源调查专项(2017FY101200)。

摘　　要：目的探讨气象和空气污染物对原发性气胸(PSP)发病的影响。方法收集2014年1月1日至2018年12月31于河北大学附属医院就诊的PSP患者的病例资料以及同时期气象和空气污染物资料。比较各季节的气象和空气污染物特征,根据PSP发病时间分为无PSP发病天和有PSP发病天2组,比较2组气象和空气污染物差异,采用logistic回归模型分析气象和空气污染物对PSP发病的影响。结果503例自发性气胸患者中有325例PSP患者,其中男274例(84.3%),女51例(15.7%)。PSP夏季高发,聚集天发病195例,占总发病人数的60.0%。平均气压、相对湿度、平均风速、日降水量、PM_(2.5)、PM_(10)、O_(3)、CO、SO_(2)、NO_(2)浓度在各季节分布不同(P值均<0.01)。与无PSP发病天组比较,有PSP发病天组平均气压(Z=-3.374,P=0.001)、NO_(2)浓度(Z=-2.539,P=0.011)较低,O_(3)浓度(Z=-3.271,P=0.001)较高。多因素回归分析显示平均气压降低为PSP发病的危险因素(OR=0.763,95%CI:0.607~0.960,P=0.021)。结论PSP发病有聚集性,与低气压有一定的联系。Objective To investigate the effect of meteorology and air pollutants on primary spontaneous pneumothorax(PSP).Methods The case data of PSP patients admitted to the Affiliated Hospital of Hebei University from January 1st,2014 to December 31st,2018,as well as meteorological and air pollutant data of the same period were collected.The characteristics of meteorology and air pollutants in each season were compared.According to the onset time of PSP,they were divided into two groups:no PSP day and PSP onset day.The differences of meteorology and air pollutants between two groups were compared.Logistic regression model was used to analyze the effect of meteorology and air pollutants on incidence of PSP.Results Among the 503 patients with spontaneous pneumothorax,325 cases were PSP,including 274 males(84.3%)and 51 females(15.7%).The incidence of PSP was higher in summer,there were 195 cases in cluster,accounting for 60.0%of the total number.There were statistical differences in atmospheric pressure,relative humidity,average wind speed,daily precipitation,PM_(2.5),PM_(10),O_(3),CO,SO_(2) and NO_(2) among different seasons(all P<0.01).Compared with no PSP day group,atmospheric pressure(Z=-3.374,P=0.001)and NO_(2)(Z=-2.539,P=0.011)were lower,O_(3)(Z=-3.271,P=0.001)was higher in PSP onset day group.Multivariate analysis revealed that decreased atmospheric pressure was an independent risk factor for PSP(OR=0.763,95%CI:0.607-0.960,P=0.021).Conclusions PSP has cluster and is associated with lower atmospheric pressure to some extent.

关 键 词：气胸 原发性 气压 气象 空气污染物 发病 

分 类 号：X51[环境科学与工程—环境工程] R561.4[医药卫生—呼吸系统]