半甲基六元瓜环和七元瓜环与三种新烟碱类农药的主客体相互作用  

Interaction of three neonicotinoid pesticides with hexamethylcucurbit[6]uriland cucurbit[7]uril

作　　者：范颖[1] 柏正坤 单培辉 高瑞晗 陶朱[1] FAN Ying;BAI Zheng-kun;SHAN Pei-hui;GAO Rui-han;TAO Zhu(Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province,Guizhou University,Guiyang 550025,China)

机构地区：[1]贵州省大环化学及超分子化学重点实验室,贵州大学,贵州贵阳550025

出　　处：《化学研究与应用》2021年第8期1519-1527,共9页Chemical Research and Application

基　　金：贵州省科技计划项目(20201Y028)资助;贵州大学引进人才科研项目(201902)资助。

摘　　要：本研究通过瓜环与化合物包结配合物的形成,建立了一种防止呋虫胺(DIN)、啶虫脒(AMP)和噻虫嗪(TMX)三种新烟碱类农药降解的策略。在中性水条件下,呋虫胺能分别与半甲基六元瓜环和七元瓜环形成计量比1∶1的主客体包结配合物,结合常数的数量级均为104。而啶虫脒和噻虫嗪因体积过大而不能被HMeQ[6]的空腔封装,仅与Q[7]形成计量比1∶1的主客体包结配合物。此外,对农药及其包结配合物进行水中释放实验的结果表明,两种瓜环的包合对呋虫胺有一定的缓释效果,而七元瓜环的包合作用对啶虫脒和噻虫嗪在水中的释放没有影响。In this work,a supramolecular strategy for preventing pesticide degradation of dinotefuran(DIN),acetamiprid(AMP)and thiamethoxam(TMX)was developed,by the encapsulation complexes formation of cucurbit[ n ]urils.DIN guest was accommodated within the cavity of HMeQ[6]and Q[7]in a ratio of 1∶1 to produce the binding constants of~10 4 mol·L^(-1) ,while AMP and TMX were too large to be encapsulated by the cavity of HMeQ[6],and therefore interacted with only Q[7]in 1∶1 ratio.Our study on the release of three pesticides demonstrated that DIN-Q[ n ]exhibit sustained-and slow-release properties.Whereas,the encapsulation of Q[7]had no effect on the release of AMP and TMX in neutral water.

关 键 词：瓜环 新烟碱类农药 包结配合物 释放 

分 类 号：O641.3[理学—物理化学]